Skip to main content
  • Book
  • © 2016

Clinical Applications of Mass Spectrometry in Drug Analysis

Methods and Protocols

Editors:

  • Includes cutting-edge methods and protocols

  • Provides step-by-step detail essential for reproducible results

  • Contains key notes and implementation advice form the experts

Part of the book series: Methods in Molecular Biology (MIMB, volume 1383)

Buying options

eBook USD 109.00
Price excludes VAT (USA)
  • ISBN: 978-1-4939-3252-8
  • Instant PDF download
  • Readable on all devices
  • Own it forever
  • Exclusive offer for individuals only
  • Tax calculation will be finalised during checkout
Softcover Book USD 139.00
Price excludes VAT (USA)
Hardcover Book USD 169.99
Price excludes VAT (USA)

This is a preview of subscription content, access via your institution.

Table of contents (27 protocols)

  1. Front Matter

    Pages i-xv
  2. Quantitation of Total Buprenorphine and Norbuprenorphine in Meconium by LC-MS/MS

    • Stephanie J. Marin, Gwendolyn A. McMillin
    Pages 59-68
  3. A Simple Liquid Chromatography Tandem Mass Spectrometry Method for Quantitation of Plasma Busulfan

    • Shuang Deng, Michael Kiscoan, Clint Frazee, Susan Abdel-Rahman, Jignesh Dalal, Uttam Garg
    Pages 79-87
  4. Cetirizine Quantification by High-Performance Liquid Chromatography Tandem Mass Spectrometry (LC-MS/MS)

    • Ada Munar, Clint Frazee, Bridgette Jones, Uttam Garg
    Pages 115-120
  5. Comprehensive Urine Drug Screen by Gas Chromatography/Mass Spectrometry (GC/MS)

    • Bheemraj Ramoo, Melissa Funke, Clint Frazee, Uttam Garg
    Pages 125-131
  6. High-Resolution Mass Spectrometry for Untargeted Drug Screening

    • Alan H. B. Wu, Jennifer Colby
    Pages 153-166

About this book

This volume describes methods and protocols for a number of drugs and toxins in a stepwise manner. Chapters in the book cover a wide array of topics such as: quantitation of Flecainide, Mexiletine, Propafenone, and Amiodarone in Serum or Plasma; quantitation of total Buprenorphine and Norbuprenorphine in Meconium; quantitation or Carisoprodol and Meprobamate in Urine; and quantitation of Tricyclic Antidepressants in Serum. Each chapter contains a brief introduction to the topic, clinical utility of the analyte(s), and useful notes to help laboratorians easily reproduce the protocols discussed. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls.

Authoritative and thorough, Clinical Applications of Mass Spectrometry in Drug Analysis: Methods and Protocols, is a great resource for laboratorians who are already using mass spectrometry or thinking of introducing this technology to their laboratories.

Keywords

  • Antibodies
  • Drug and Toxins Analyses
  • Mass Spectrometry (MS)
  • Multi-Component Analysis
  • Toxin analysis

Editors and Affiliations

  • Dept of Pathology & Lab Medicine, Children's Mercy Hospitals & Clinics, Kansas City, USA

    Uttam Garg

Bibliographic Information

  • Book Title: Clinical Applications of Mass Spectrometry in Drug Analysis

  • Book Subtitle: Methods and Protocols

  • Editors: Uttam Garg

  • Series Title: Methods in Molecular Biology

  • DOI: https://doi.org/10.1007/978-1-4939-3252-8

  • Publisher: Humana New York, NY

  • eBook Packages: Springer Protocols

  • Copyright Information: Springer Science+Business Media New York 2016

  • Hardcover ISBN: 978-1-4939-3251-1

  • Softcover ISBN: 978-1-4939-8006-2

  • eBook ISBN: 978-1-4939-3252-8

  • Series ISSN: 1064-3745

  • Series E-ISSN: 1940-6029

  • Edition Number: 1

  • Number of Pages: XV, 272

  • Number of Illustrations: 14 b/w illustrations, 27 illustrations in colour

  • Topics: Pharmacology

  • Industry Sectors: Biotechnology, Chemical Manufacturing, Consumer Packaged Goods, Health & Hospitals, Pharma

Buying options

eBook USD 109.00
Price excludes VAT (USA)
  • ISBN: 978-1-4939-3252-8
  • Instant PDF download
  • Readable on all devices
  • Own it forever
  • Exclusive offer for individuals only
  • Tax calculation will be finalised during checkout
Softcover Book USD 139.00
Price excludes VAT (USA)
Hardcover Book USD 169.99
Price excludes VAT (USA)