Cytochrome P450

  • John B. Schenkman
  • Helmut Greim

Part of the Handbook of Experimental Pharmacology book series (HEP, volume 105)

Table of contents

  1. Biosynthetic Forms of Cytochrome P450

    1. P. C. White
      Pages 693-703
    2. K. Wikvall
      Pages 705-718
    3. K. A. White, M. A. Marletta
      Pages 719-728
  2. Back Matter
    Pages 729-739

About this book


In this book the editors have brought together the widest group of investigators of the cytochrome P450 superfamily in order to present complete and right up-to-date coverage of this important enzyme system. The authors describe and analyze the components of the enzyme system, the reaction mechanisms involved, and the evolution and nomenclature of this superfamily of enzymes. They also describe the hepatic microsomal enzyme in a large number of species, from mammalian to birds and fish, to plants and unicellular organisms. The different P450 forms in different tissues of the mammalian system are also treated. Regulatory factors of P450 expression receive considerable attention, as do studies on the mechanism of interaction of the microsomal monooxygenase system components. Of particular interest to the reader are, for the first time, a compilation of chapters dedicated to forms of cytochrome P450 involved in steroid hormone biosynthesis. This volume presents the most complete survey of the cytochrome P450 field. It will allow recognition and understanding of the very wide implications this enzyme system has on life processes.


biosynthesis cytochrome P450 enzyme enzymes hormone hormones steroid synthesis

Editors and affiliations

  • John B. Schenkman
    • 1
  • Helmut Greim
    • 2
  1. 1.Department of Pharmacology, MC 1505University of Connecticut Health CenterFarmingtonUSA
  2. 2.Institut für ToxikologieGesellschaft für Strahlen- und Umweltforschung mbHNeuherbergFed. Rep. of Germany

Bibliographic information

  • DOI
  • Copyright Information Springer-Verlag Berlin Heidelberg 1993
  • Publisher Name Springer, Berlin, Heidelberg
  • eBook Packages Springer Book Archive
  • Print ISBN 978-3-642-77765-3
  • Online ISBN 978-3-642-77763-9
  • Series Print ISSN 0171-2004
  • Series Online ISSN 1865-0325
  • Buy this book on publisher's site
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