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Cytochromes P450 in Genetically Engineered Cell Cultures: The Gene Technological Approach

  • J. Doehmer
  • H. Greim
Part of the Handbook of Experimental Pharmacology book series (HEP, volume 105)

Abstract

Molecular cloning of genes encoding cytochromes P450 followed by heterologous expression in various systems is being successfully applied in multi-faceted studies of cytochromes P450. The application of modern molecular biology techniques is especially indicated for complex systems such as the cytochromes P450 in order to sort out a particular isoform without the need for tedious purification.

Keywords

Stable Expression P450 Reductase Human Cytochrome Cytochrome P450 Reductase Human Lymphoblastoid Cell Line 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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© Springer-Verlag Berlin Heidelberg 1993

Authors and Affiliations

  • J. Doehmer
  • H. Greim

There are no affiliations available

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