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Induction of Cytochromes P450 1 and P450 2 by Xenobiotics

  • E. Bresnick
Chapter
Part of the Handbook of Experimental Pharmacology book series (HEP, volume 105)

Abstract

It has long been known that metabolic activation of a number of xenobiotics including the polycyclic aromatic hydrocarbons is required prior to eliciting mutagenic, teratogenic or carcinogenic properties. This activation is conducted in part by cytochrome P450 mediated pathways.

Keywords

CYP2B2 Gene Polycyclic Hydrocarbon Aryl Hydrocarbon Hydroxylase Hepatic Microsomal Cytochrome Phenobarbital Induction 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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  • E. Bresnick

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