Muscle Relaxants

Physiologic and Pharmacologic Aspects

  • Kazuaki Fukushima
  • Ryoichi Ochiai

Table of contents

  1. Front Matter
    Pages II-XIX
  2. History of Muscle Relaxants

  3. The Neuromuscular Junctions — Update

    1. Front Matter
      Pages 17-17
    2. W. C. Bowman
      Pages 19-30
    3. Frank G. Standaert
      Pages 31-36
    4. Makoto Endo
      Pages 48-48
  4. Current Basic Experimental Works Related to Neuromuscular Blockade in Present and Future

  5. Current Clinical Experimental Works Related to Neuromuscular Blockade in Present and Future

    1. Front Matter
      Pages 91-91
    2. Ronald D. Miller
      Pages 93-94
    3. James E. Caldwell
      Pages 95-104
    4. Rajinder K. Mirakhur
      Pages 105-110
  6. Basic Aspects of Neuromuscular Junction

    1. Front Matter
      Pages 115-115
    2. W. C. Bowman
      Pages 117-127
    3. Darwin K. Berg, William G. Conroy, Roderick A. Corriveau, Phyllis C. Pugh, Margaret M. Rathouz, Suzanne J. Romano et al.
      Pages 128-134
    4. C. Spencer Yost
      Pages 135-141
    5. Hajime Suzuki
      Pages 142-149
    6. Yoshiaki Kidokoro
      Pages 150-153
  7. Onset of Action

  8. Relaxants in ICU

  9. Pharmacokinetics, Metabolism, and Metabolites

    1. Front Matter
      Pages 187-187
    2. John J. Savarese, Matthew R. Belmont, Cynthia A. Lien
      Pages 189-193
    3. Johannes H. Proost, J. Mark K. H. Wierda, Dirk K. F. Meijer
      Pages 205-212
  10. Uses in Special Groups

  11. Monitoring

    1. Front Matter
      Pages 255-255
    2. Naoyuki Ueda
      Pages 262-265
  12. Drug Interactions

    1. Front Matter
      Pages 267-267
    2. Hideo Nagashima, E. Sylvester Vizi, Francis F. Foldes
      Pages 275-279

About these proceedings


At the Fifth International Neuromuscular Meeting held in Tokyo in 1994, leading experts in the field came together to discuss the physiology and pharmacology of neuromuscular receptor sites and neuromuscular blocking agents (NBAs). The proceedings of the meeting present a review of the history of muscle relaxants and a comprehensive examination of recent research, with a primary focus on clinical considerations. Among the topics covered by specific chapters are aspects of the neuromuscular junction (NMJ), pharmacokinetics, metabolism and metabolites of neuromuscular blocking agents, and drug interaction. Presenting the most up-to-date knowledge of the physiology and pharmacology of the NMJ and NBAs, this volume will be highly valuable to clinicians and researchers in anesthesiology, physiology, and pharmacology.


Acetylcholin Histamin Nicotin calcium drug kidney kinetics metabolism pharmacodynamics pharmacokinetics pharmacology physiology research tissue transplantation

Editors and affiliations

  • Kazuaki Fukushima
    • 1
  • Ryoichi Ochiai
    • 1
  1. 1.Department of AnesthesiologyKeio University School of MedicineShinjuku-ku, Tokyo 160Japan

Bibliographic information

Industry Sectors
Health & Hospitals