Mechanisms of Action of Reversal Agents

  • W. C. Bowman
Conference paper


Most types of reversal agents act mainly by increasing the concentration of acetylcholine available in the junctional cleft to compete with the nondepolarizing neuromuscular blocking drugs. Hence, it is worthwhile first to consider the dynamics of the actions both of the neurotransmitter (acetylcholine) and of the clinically-used nondepolarizing blocking drugs.


Blocking Drug Reversal Agent Endplate Potential Esteratic Site Anticholinesterase Drug 
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Copyright information

© Springer Japan 1995

Authors and Affiliations

  • W. C. Bowman
    • 1
  1. 1.Department of Physiology and PharmacologyUniversity of StarthclydeGlasgowUK

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