Overview
- Editors:
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Michael E. Maragoudakis
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University of Patras Medical School, Patras, Greece
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Pietro M. Gullino
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University of Torino Medical School, Torino, Italy
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Peter I. Lelkes
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University of Wisconsin Medical School, Milwaukee, USA
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Table of contents (37 chapters)
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Regulation of Angiogenesis
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- Victor W. M. van Hinsbergh, Roeland Hanemaaijer, Pieter Koolwijk
Pages 171-181
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Angiogenesis and Disease States
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- Michael Höckel, Karlheinz Schlenger, Renate Frischmann-Berger, Sabine Berger, Peter Vaupel
Pages 193-207
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- S. Kumar, J. Ponting, P. Rooney, P. Kumar, D. Pye, M. Wang
Pages 219-231
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- W. D. Thompson, J. E. H. Wang, S. J. Wilson, N. Ganesalingam
Pages 245-252
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- John W. Fenton II, Frederick A. Ofosu
Pages 253-263
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- Carl G. Hellerqvist, Gary B. Thurman, Bruce A. Russell, David L. Page, Gerald E. York, Yue-Fen Wang et al.
Pages 265-269
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- Nicola Mongelli, Maria Grandi
Pages 271-276
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Methodology
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- Wanda Auerbach, Robert Auerbach
Pages 283-289
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- E. Papadimitriou, B. R. Unsworth, M. E. Maragoudakis, P. I. Lelkes
Pages 291-305
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- Peter I. Lelkes, Dawn M. Chick, Mark M. Samet, Viktor Nikolaychik, Gregory A. Thomas, Robert L. Hammond et al.
Pages 321-331
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- Frank Arnold, H. Brem, G. Tamavokopulis, D. Tsakayannis, I. Gresser, A. Budson et al.
Pages 333-358
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Back Matter
Pages 360-372
About this book
Angiogenesis is a multistep process, which involves activation, proliferation and directed migration of endothelial cells to form new capillaries from existing vessels. Under physiological conditions, in the adult organisms angiogenesis is extremely slow, yet it can be activated for a limited time only in situations such as ovulation or wound healing. In a number of disease states, however, there is a derangement of angiogenesis, which can contribute to the pathology of these conditions. Hence, understanding the molecular biology of endothelial cell activation and differentiation and the mechanisms involved in the regulation of angiogenesis, could explain the derangement in disease states and also provide the basis for developing promoters or suppressors of angiogenesis for clinical applications. This book contains the proceedings of the NATO Advanced Study Institute on "Angiogenesis: Molecular Biology, Oinical Aspects" held in Rhodes, Greece, from June 16-27, 1993. This meeting was a comprehensive review of the various aspects of angiogenesis such as embryonic development, endothelial cell heterogeneity and tissue specificity, molecular biology of endothelial cell, mechanisms for the regulation of angiogenesis, disease states in which angiogenesis is involved and potential application of promoters or suppressors of angiogenesis. The presentations and discussions of the meeting provided an opportunity for investigators from many different areas of basic science and medicine to exchange information, evaluate the present status and provide future research directions in the field of angiogenesis.
Editors and Affiliations
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University of Patras Medical School, Patras, Greece
Michael E. Maragoudakis
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University of Torino Medical School, Torino, Italy
Pietro M. Gullino
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University of Wisconsin Medical School, Milwaukee, USA
Peter I. Lelkes