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Natural Compounds as Drugs

Volume II

  • Frank Petersen
  • René Amstutz

Part of the Progress in Drug Research book series (PDR, volume 66)

Table of contents

  1. Front Matter
    Pages i-x
  2. Axel A. Brakhage, Julia Schuemann, Sebastian Bergmann, Kirstin Scherlach, Volker Schroeckh, Christian Hertweck
    Pages 1-12
  3. Andres Lopez, Ainslie B. Parsons, Corey Nislow, Guri Giaever, Charles Boone
    Pages 237-271
  4. Yuhta Masuoka, Nobuaki Shindoh, Noriaki Inamura
    Pages 335-359
  5. Peter C. Hiestand, Martin Rausch, Daniela Piani Meier, Carolyn A. Foster
    Pages 361-381
  6. Back Matter
    Pages 423-427

About this book

Introduction

The use of drug substances derived from plants, fungi, bacteria, and marine organisms has a long tradition in medicine. Together with their derivatives, and synthetic compounds deduced from natural product precursors, they represent a major part of today's pharmaceutical market.

Within the fast developing discipline of molecular biology, natural products also play an important role as tool compounds in pathway screening and validation of target identification concepts. They provide innovative opportunities in drug discovery, leading to a detailed understanding of biological pathways and revealing the functions of involved enzymes or receptors.

This book highlights new trends and aspects in natural products research. It discusses the biodiversity-driven approaches which are now of eminent importance in natural products research, addressing the question why natural products display such a complex chemical information, what makes them often unique and what their characteristics are. Practical questions such as supply of natural substances and production optimization strategies are also covered.

Keywords

bacteria cancer drug drug discovery drug research enzymes fermentation high throughput screening lead natural product pharmacology receptor research screening synthesis

Editors and affiliations

  • Frank Petersen
    • 1
  • René Amstutz
    • 1
  1. 1.Novartis Pharma AGBaselSwitzerland

Bibliographic information

Industry Sectors
Pharma
Chemical Manufacturing
Biotechnology
Consumer Packaged Goods