Artemisinin — an innovative cornerstone for anti-malaria therapy

  • Thomas Kuhn 
  • Ying Wang 
Part of the Progress in Drug Research book series (PDR, volume 66)


Artemisinin-based Combination Therapies (ACT) are recommended by the World Health Organization (WHO) to treat especially multidrug resistant forms of malaria, as currently used medications have become increasingly ineffective. In this chapter, the discovery of artemisinin from Traditional Chinese Medicine and its further development to ACT are reviewed. It is highlighted how the complex supply chain to the naturally occurring endoperoxide artemisinin, required to produce ACT-based drugs, was established; thus addressing the significant therapeutic needs and high demands for the medication.


Supply Chain Antimalarial Drug ARTESU NATE Aflatoxin Contamination ARTEMETHER LUMEFANTRINE 


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Copyright information

© Birkhäuser Verlag, Basel (Switzerland) 2007

Authors and Affiliations

  • Thomas Kuhn 
    • 1
  • Ying Wang 
    • 2
  1. 1.Global Chemical OperationsSwitzerland
  2. 2.Natural Product Unit, Novartis Institutes for Biomedical ResearchNovartis Pharma AGBaselSwitzerland

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