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The Molecular Biology of Autoimmune Disease

  • Conference proceedings
  • © 1990

Overview

Editors:
  1. Andrew G. Demaine

    1. Department of Medicine, King’s College School of Medicine, London, UK

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  2. J-Paul Banga

    1. Department of Medicine, King’s College School of Medicine, London, UK

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    You can also search for this editor in PubMed   Google Scholar

  3. Alan M. McGregor

    1. Department of Medicine, King’s College School of Medicine, London, UK

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Part of the book series: Nato ASI Subseries H: (ASIH, volume 38)

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Table of contents (37 papers)

  1. Interaction of Auto-Antigen, MHC and T Cell Receptor

    1. Functional Dissociation of T Cell Sites; Immunogenic, Antigenic and Pathogenic Sites

      • Dale S. Gregerson, Steven P. Fling, Wesley F. Obritsch, Carmen F. Merryman, Larry A. Donoso
      Pages 209-219

    2. Autoreactive Cloned T Cell Lines in Murine Insulin-Dependent Diabetes Mellitus

      • Eva-Pia Reich, Satyajit Rath, Robert Sherwin, Hugh McDevitt, Charles A. Janeway Jr.
      Pages 221-234

    3. Chairman’s Summing up

      • C. A. Janeway
      Pages 235-241

  2. Immunogenetics and Autoimmunity

    1. HLA Class II Sequence Polymorphism and Autoimmunity

      • Henry A. Erlich, Teodorica L. Bugawan, Stephen J. Scharf
      Pages 243-250

    2. HLA-DQ and Diabetes Mellitus: A Genetic and Structural Paradigm for Models of Disease Susceptibility

      • Gerald T. Nepom, David M. Robinson
      Pages 251-262

    3. A Single Recessive Non-MHC Diabetogenic Gene Determines the Development of Insulitis in NOD Mice

      • Masakazu Hattori, Masahiro Fukuda, Fumihiko Horio
      Pages 263-272

    4. Autoimmunity — More Than the MHC?

      • A. G. Demaine, B. A. Millward, N. Willcox, A. Thompson, J. Newsom-Davis
      Pages 273-284

    5. Chairman’s Summing up

      • G. S. Eisenbarth
      Pages 285-289

  3. Clinical and Experimental Autoimmunity

    1. The Idiotypic Network in Experimental Autoimmune Thyroiditis (EAT): Towards a New Conception of Autoimmune Reactivity

      • C. Bédin, B. Texier, C. Roubaty, J. Charreire
      Pages 291-300

    2. Factors Affecting Diabetes in Rodent Models of Insulin Dependent Diabetes Mellitus

      • L. O’Reilly, P. R. Hutchings, N. Parish, E. Simpson, T. Tomonari, T. Lund et al.
      Pages 301-311

    3. Cells and Immune Processes Contributing to Pancreatic Islet Inflammation

      • H. Kolb, V. Kolb-Bachofen
      Pages 313-323

    4. Synopsis of Paper Entitled “Ir Gene Expression, Antigen Processing and Autoantigen Characterization in Autoimmune Diseases of the Nervous System”

      • H. Wekerle
      Pages 325-331

    5. Mechanisms of Resistance to Autoimmune Disease Induced by T-Cell Vaccination

      • Ansgar W. Lohse, Irun R. Cohen
      Pages 333-342

  4. Clinical and Experimental Autoimmunity II

    1. T Cell Reactivity to Acetylcholine Receptor in Myasthenia Gravis

      • John Newsom-Davis, Gillian Harcourt, David Beeson, Norbert Sommer, Angela Vincent, Nick Willcox
      Pages 343-350

    2. Type I Diabetes as a “Mendelian” and “Regulated” Immune Process

      • E. Russo, R. A. Jackson, F. Dotta, M. A. Lipes, L. Castano, J. Zielasek et al.
      Pages 351-362

    3. The Cloning Road to the TSH Receptor and Autoimmune Graves’ Disease

      • Leonard D. Kohn, Takashi Akamizu, Motoyasu Saji, Shoichero Ikuyama, Shashikumar Bellur, Kazuo Tahara
      Pages 363-378

    4. Thyroid Peroxidase: Studies on Auto-Antibody Recognition, Gene Expression and Secondary Structure Prediction

      • Kate S. Collison, D. Mahadevan, P. S. Barnett, Nan D. Doble, R. W. S. Tomlinson, J.-P. Banga et al.
      Pages 379-390

  5. ESCI Boerhaave Lecture for 1989

    1. Sjogren’s Syndrome, a Model to Study Autoimmunity and Malignancy

      • H. M. Moutsopoulos, P. Youinou
      Pages 391-398

  6. Back Matter

    Pages 399-406
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Keywords

About this book

Autoimmune diseases are common and often associated with considerable morbidity or - in diseases such as IDDM, myasthenia gravis and multiple sclerosis - mortality. In this volume, experts of international stature in basic science and clinical medicine with a common interest in understanding the normal and aberrant immune response present their experiences. It was their intention to fur- ther the understanding of potential clinical application of scientific observations and to help to comprehend the huge amount of results in autoimmunity research.

Editors and Affiliations

  • Department of Medicine, King’s College School of Medicine, London, UK

    Andrew G. Demaine, J-Paul Banga, Alan M. McGregor

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