The Idiotypic Network in Experimental Autoimmune Thyroiditis (EAT): Towards a New Conception of Autoimmune Reactivity
Thyroiditis is an autoimmune disorder resulting in hypofunction of the thyroid gland because of its damage. This disease occurs either spontaneously in various species of animals including the OS chicken or the Buffalo rat, or experimentally after immunization of susceptible animals with thyroglobulin (Tg) or defined Tg tryptic fragments. Transfer of experimental autoimmune thyroiditis (EAT) can also be achieved by Tg specific helper T cell lines or clones (for review, see J. Charreire, 1989).
KeywordsExperimental Autoimmune Encephalomyelitis None None Internal Image Idiotypic Network Pathogenic Epitope
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