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  • © 2007

General Principles of Tumor Immunotherapy

Basic and Clinical Applications of Tumor Immunology

  • Describes how the immune system can be harnessed to recognize and kill tumor cells

  • Illustrates how current advances in immunology are being used in tumor immunotherapy

  • Details the rationale and indications for tumor immunotherapy

  • Discusses some of the current obstacles to successful tumor immunotherapy

  • Brings together the world’s leading experts in tumor immunology

Buying options

eBook USD 149.00
Price excludes VAT (USA)
  • ISBN: 978-1-4020-6087-8
  • Instant PDF download
  • Readable on all devices
  • Own it forever
  • Exclusive offer for individuals only
  • Tax calculation will be finalised during checkout
Softcover Book USD 199.99
Price excludes VAT (USA)
Hardcover Book USD 279.99
Price excludes VAT (USA)

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Table of contents (21 chapters)

  1. Front Matter

    Pages I-XII
  2. General Principles of Tumor Immunology

    1. Front Matter

      Pages 1-1
    2. Tumor Antigens

      • Michael A. Morse, Timothy M. Clay, H Kim Lyerly
      Pages 17-31
    3. T Cells and Antigen Recognition

      • Leisha A. Emens
      Pages 33-53
    4. Immunomodulatory Molecules of the Immune System

      • Yvonne M. Saenger, Robert R. Jenq, Miguel-Angel Perales
      Pages 67-121
    5. HLA Class I Antigen Abnormalities in Tumors

      • Barbara Seliger, Soldano Ferrone
      Pages 123-144
    6. The Local Tumor Microenvironment

      • Theresa L. Whiteside
      Pages 145-167
  3. Tumor Vaccines

    1. Front Matter

      Pages 169-169
    2. Peptide and Protein Vaccines for Cancer

      • Raymond M. Wong, Jeffrey S. Weber
      Pages 171-192
    3. DNA Vaccines Against Cancer

      • Adam D. Cohen, Jedd D. Wolchok
      Pages 193-215
    4. Recombinant Viral and Bacterial Vaccines

      • Douglas W. Grosenbach, Jarett Feldman, Jeffrey Schlom, Scott I. Abrams
      Pages 217-250
    5. Dendritic Cell Vaccines

      • Sylvia Adams, Nina Bhardwaj, David W. O’Neill
      Pages 251-274
    6. Whole Cell Vaccines

      • Mark B. Faries, Donald L. Morton
      Pages 275-295
    7. Carbohydrate Vaccines Against Cancer

      • Philip O. Livingston, Govind Ragupathi
      Pages 297-317
  4. Passive Immunotherapy Approaches

    1. Front Matter

      Pages 319-319
    2. Monoclonal Antibody Therapy of Cancer

      • Joseph G. Jurcic, Deborah A. Mulford, David A. Scheinberg
      Pages 321-342
    3. Checkpoint Blockade and Combinatorial Immunotherapies

      • Karl S. Peggs, Sergio A. Quezada, James P. Allison
      Pages 363-390

About this book

"General Principles of Tumor Immunotherapy: Basic and Clinical Applications of Tumor Immunology" brings together the world’s leading authorities on tumor immunology. This book describes the basic immunology principles that form the foundation of understanding how the immune system recognizes and rejects tumor cells. The role of the innate and adaptive immune responses is discussed and the implications of these responses for the design of clinical strategies to combat cancer are illustrated through both experimental clinical trials and review of current standard of care therapeutic agents. This information will be invaluable to both students of immunology and cancer research and practicing physicians who have patients with cancer. The book provides a comprehensive overview of the field, demonstrates how advances in basic immunology can and are being applied to cancer, and describes the current status of approved immunotherapy regimens.

Keywords

  • Antigen
  • DNA
  • bacteria
  • cancer
  • cell
  • clinical trial
  • immune response
  • immunity
  • immunology
  • immunotherapy
  • interferon
  • peptides
  • research
  • tumor
  • vaccine
  • surgical oncology

Editors and Affiliations

  • The Tumor Immunology Laboratory, Division of Surgical Oncology, Columbia University, New York

    Howard L. Kaufman

  • Department of Medicine, Memorial Sloan-Kettering Cancer Center, Weill Medical College of Cornell University, New York

    Jedd D. Wolchok

Bibliographic Information

Buying options

eBook USD 149.00
Price excludes VAT (USA)
  • ISBN: 978-1-4020-6087-8
  • Instant PDF download
  • Readable on all devices
  • Own it forever
  • Exclusive offer for individuals only
  • Tax calculation will be finalised during checkout
Softcover Book USD 199.99
Price excludes VAT (USA)
Hardcover Book USD 279.99
Price excludes VAT (USA)