Skip to main content
SpringerLink
Log in

A Perspective on Cancer Immunology and Immunotherapy

  • Chapter
General Principles of Tumor Immunotherapy

  • 1174 Accesses

This is a preview of subscription content, log in via an institution to check access.

Access this chapter

Log in via an institution
Chapter
USD 29.95
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
eBook
USD 169.00
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
Softcover Book
USD 219.99
Price excludes VAT (USA)
  • Compact, lightweight edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info
Hardcover Book
USD 219.99
Price excludes VAT (USA)
  • Durable hardcover edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Purchases are for personal use only

Institutional subscriptions

Preview

Unable to display preview. Download preview PDF.

Unable to display preview. Download preview PDF.

References

  1. Jenner, E., 1801. An inquiry into the causes and effects of the Variolae Vacciniae, a disease discovered in some of the western counties of England, particularly Gloucestershire, and known by the name of the cow-pox, Third edition, D.N. Shury, London.

    Google Scholar 

  2. Coley, W. B., 1893, The treatment of malignant tumors by repeated inoculations of erysipelas with a report of ten original cases, Am. J. Med. Sci. 105:487–511.

    Article  Google Scholar 

  3. Hall, S. S., 1997. A Commotion in the Blood. Life, Death and the Immune System, Henry Holt & Co., New York.

    Google Scholar 

  4. Gratia, A. and Linz, R., 1931, Le phénoméne de Schwartzman dans le sarcome du Cobaye, CR Séances Soc. Biol. Ses. Fil. 108:427–428.

    Google Scholar 

  5. Shear, M. J., Turner, F. C., Perrault, A. and Shovelton, T., 1943, Chemical treatment of tumors. V. Isolation of the hemorrhage-producing fraction from Serratia marcescens (Bacillus prodigiosus) culture filtrate, J. Natl. Cancer Inst. 4:81–97.

    CAS  Google Scholar 

  6. Shear, M. J., 1944, Chemical treatment of tumors. IX. Reactions of mice with primary subcutaneous tumors to injection of a hemorrhage-producing bacterial polysaccharide, J. Natl. Cancer Inst. 4:461–476.

    CAS  Google Scholar 

  7. Algire, G. H., Legallais, F. Y. and Anderson, B. F., 1952, Vascular reactions of normal and malignant tissues in vivo. V. Role of hypertension in action of bacterial polysaccharide on tumors, J. Nat. Cancer Inst. 12:1279–1295.

    PubMed  CAS  Google Scholar 

  8. Nowotny, A., 1969, Molecular aspects of endotoxic reactions, Bacteriol. Rev. 33:72–98.

    PubMed  CAS  Google Scholar 

  9. Parr, I., Wheeler, E. and Alexander, P., 1973, Similarities of the antitumor actions of endotoxin, lipid A and double-stranded RNA, Br. J. Cancer. 27:370–389.

    PubMed  CAS  Google Scholar 

  10. Carswell, E. A., Old, L. J., Kassel, R. L., Green, S., Fiore, N. and Williamson, B., 1975, An endotoxin-induced serum factor that causes necrosis of tumors, Proc. Natl. Acad. Sci. U. S. A. 72:3666–3670.

    Google Scholar 

  11. Janeway, C. A., Jr., 1989, Approaching the asymptote? Evolution and revolution in immunology, Cold Spring Harb. Symp. Quant. Biol. 54 Pt 1:1–13.

    Google Scholar 

  12. Amos, D. B., 1986, Recollections of Dr. Peter Gorer, Immunogenetics. 24:341–344.

    Article  PubMed  CAS  Google Scholar 

  13. Ehrlich, P., 1897, Die Wertbestimmung des Diphterieheilserums und deren theoretische Grundlagen, Klinische Jahrbucher. 6:299–326.

    Google Scholar 

  14. Ehrlich, P., 1906. Collected Studies on Immunity, John Wiley & Sons, New York.

    Google Scholar 

  15. Landsteiner, K., 1901, Ueber Agglutinationserscheinungen normalen menschlichen Blutes, Wein Klin. Wochenschr. 14:1132–1134.

    Google Scholar 

  16. von Dungern, E. and Hirszfeld, L., 1911, Ueber gruppenspezifische Strukturen des Blutes III., Zeitschrift für Immunologische Forschung. 8:526–562.

    CAS  Google Scholar 

  17. Ehrlich, P. and Morgenroth, J., 1901, Ueber haemolysin, Berliner Klin. Wochenschr. 38:569.

    Google Scholar 

  18. Ehrlich, P. and Morgenroth, J., 1957. On haemolysins: Third and fifth communications, Pergamon Press, London.

    Google Scholar 

  19. Little, C. C., 1914, A possible Mendelian explanation for a type of an inheritance apparently non-Mendelian in nature, Science. 40:904–906.

    Article  PubMed  Google Scholar 

  20. Little, C. C., 1941. The genetics of tumor transplantation, Dover, New York.

    Google Scholar 

  21. Gorer, P. A., 1937a, Further studies on antigenetic differences in mouse erythrocytes, J. Pathol. Bacteriol. 44:31–36.

    Article  Google Scholar 

  22. Gorer, P. A., 1937b, The genetic and antigenetic basis of tumour transplantation, J. Pathol. Bacteriol. 44:691–697.

    Article  Google Scholar 

  23. Gorer, P. A., 1938, The antigenic basis of tumour transplantation, J. Pathol. Bacteriol. 44:231–252.

    Article  Google Scholar 

  24. Gorer, P. A., 1959, The immunogenetics of cancer, Jaarb. K. Ned. Bot. Ve. 9:90–97.

    CAS  Google Scholar 

  25. Gorer, P. A., Lyman, S. and Snell, G. D., 1948, Studies on the genetic and antigenic basis of tumor transplantation: linkage between a histocompatibility gene and “fused” in mice, Proc. Royal Soc. London Ser. B. 135:499–505.

    Google Scholar 

  26. Robinson, J., Waller, M. J., Parham, P., de Groot, N., Bontrop, R., Kennedy, L. J., Stoehr, P. and Marsh, S. G., 2003, IMGT/HLA and IMGT/MHC: sequence databases for the study of the major histocompatibility complex, Nucleic Acids Res. 31:311–314.

    Article  PubMed  CAS  Google Scholar 

  27. Gross, L., 1950, Susceptibility of suckling-infant, and resistance of adult, mice of the C3H and of the C57 lines to inoculation with AKR leukemia, Cancer. 3:1073–1087.

    Article  PubMed  CAS  Google Scholar 

  28. Foley, E. J., 1953, Antigenic properties of methylcholanthrene-induced tumors in mice of the strain of origin, Cancer Res. 13:835–837.

    PubMed  CAS  Google Scholar 

  29. Prehn, R. T. and Main, J. M., 1957, Immunity to methylcholanthrene-induced sarcomas, J. Natl. Cancer Inst. 18:769–778.

    PubMed  CAS  Google Scholar 

  30. Klein, G., 2001, The strange road to the tumor-specific transplantation antigens (TSTAs), Cancer Immunity. 1:6.

    PubMed  CAS  Google Scholar 

  31. Basombrio, M. A., 1970, Search for common antigenicities among twenty-five sarcomas induced by methylcholanthrene, Cancer Res. 30:2458–2462.

    PubMed  CAS  Google Scholar 

  32. Burnet, F., 1970, The concept of immunological surveillance, Prog. Exp. Tumor Res. 13:1–27.

    PubMed  CAS  Google Scholar 

  33. Thomas, L., 1982, On immunosurveillance in human cancer, Yale J. Biol. Med. 55:329–333.

    PubMed  CAS  Google Scholar 

  34. Hewitt, H. B., Blake, E. R. and Walder, A. S., 1976, A critique of the evidence for active host defense against cancer, based on personal studies of 27 murine tumours of spontaneous origin, Br. J. Cancer. 33:241–259.

    PubMed  CAS  Google Scholar 

  35. Stutman, O., 1974, Tumor development after 3-methylcholanthrene in immunologically deficient athymic-nude mice, Science. 183:534–536.

    Article  PubMed  CAS  Google Scholar 

  36. Stutman, O., 1975, Immunodepression and malignancy, Adv Cancer Res. 22:261–422.

    Article  PubMed  CAS  Google Scholar 

  37. Pel, A. V., Vessiere, F. and Boon, T., 1983, Protection against two spontaneous mouse leukemias conferred by immunogenic variants obtained by mutagenesis, J. Exp. Med. 157:1992–2000.

    Article  PubMed  Google Scholar 

  38. Dye, E. S. and North, R. J., 1981, T cell-mediated immunosuppression as an obstacle to adoptive immunotherapy of the P815 mastocytoma and its metastases, J. Exp. Med. 154:1033–1042.

    Article  PubMed  CAS  Google Scholar 

  39. North, R. J., 1982, Cyclophosphamide-facilitated adoptive immunotherapy of an established tumor depends on elimination of tumor-induced suppressor T cells, J. Exp. Med. 155:1063–1074.

    Article  PubMed  CAS  Google Scholar 

  40. Mills, C. D. and North, R. J., 1983, Expression of passively transferred immunity against an established tumor depends on generation of cytolytic T cells in recipient. Inhibition by suppressor T cells, J. Exp. Med. 157:1448–1460.

    Article  PubMed  CAS  Google Scholar 

  41. Bursuker, I. and North, R. J., 1984, Generation and decay of the immune response to a progressive fibrosarcoma. II. Failure to demonstrate postexcision immunity after the onset of T cell-mediated suppression of immunity, J. Exp. Med. 159:1312–1321.

    Article  PubMed  CAS  Google Scholar 

  42. North, R. J. and Bursuker, I., 1984, Generation and decay of the immune response to a progressive fibrosarcoma. I. Ly-1+2- suppressor T cells down-regulate the generation of Ly-1-2+ effector T cells, J. Exp. Mede. 159:1295–1311.

    Article  CAS  Google Scholar 

  43. Bursuker, I. and North, R. J., 1985, Suppression of generation of concomitant antitumor immunity by passively transferred suppressor T cells from tumor-bearing donors, Cancer Immunology & Immunotherapy. 19:215–218.

    CAS  Google Scholar 

  44. Dunn, G. P., Old, L. J. and Schreiber, R. D., 2004, The immunobiology of cancer immunosurveillance and immunoediting, Immunity. 21:137–148.

    Article  PubMed  CAS  Google Scholar 

  45. Pukel, C. S., Lloyd, K. O., Travassos, L. R., Dippold, W. G., Oettgen, H. F. and Old, L. J., 1982, GD3, a prominent ganglioside of human melanoma. Detection and characterisation by mouse monoclonal antibody, J. Exp. Med. 155:1133–1147.

    Article  PubMed  CAS  Google Scholar 

  46. De Plaen, E., Lurquin, C., Van Pel, A., Mariame, B., Szikora, J. P., Wolfel, T., Sibille, C., Chomez, P. and Boon, T., 1988, Immunogenic (tum-) variants of mouse tumor P815: cloning of the gene of tum- antigen P91A and identification of the tum- mutation, Proc. Natl. Acad. Sci. U. S. A. 85:2274–2278.

    Article  PubMed  Google Scholar 

  47. Vijayasaradhi, S., Bouchard, B. and Houghton, A. N., 1990, The melanoma antigen gp75 is the human homologue of the mouse b (brown) locus gene product, J. Exp. Med. 171:1375–1380.

    Article  PubMed  CAS  Google Scholar 

  48. van der Bruggen, P., Traversari, C., Chomez, P., Lurquin, C., De Plaen, E., Van den Eynde, B., Knuth, A. and Boon, T., 1991, A gene encoding an antigen recognized by cytolytic T lymphocytes on a human melanoma, Science. 254:1643–1647.

    Article  PubMed  Google Scholar 

  49. Bowne, W. B., Srinivasan, R., Wolchok, J. D., Hawkins, W. G., Blachere, N. E., Dyall, R., Lewis, J. J. and Houghton, A. N., 1999, Coupling and uncoupling of tumor immunity and autoimmunity, J. Exp. Med. 190:1717–1722.

    Article  PubMed  CAS  Google Scholar 

  50. Mazmanian, S. K., Liu, C. H., Tzianabos, A. O. and Kasper, D. L., 2005, An immunomodulatory molecule of symbiotic bacteria directs maturation of the host immune system, Cell. 122:107–118.

    Article  PubMed  CAS  Google Scholar 

  51. Houghton, A. N., 1994, Cancer antigens: Immune recognition of self and altered self, J. Exp. Med. 180:1–4.

    Article  PubMed  CAS  Google Scholar 

  52. Matzinger, P., 1994, Tolerance, danger, and the extended family, Ann. Rev. Immunol. 12:991–1045.

    CAS  Google Scholar 

Download references

Author information

Authors and Affiliations

  1. Swim Across America Laboratory, Memorial Sloan-Kettering Cancer Center, 1275 York Ave, New York, NY 10021

    Alan N. Houghton

Authors
  1. Alan N. Houghton
    View author publications

    You can also search for this author in PubMed Google Scholar

Editor information

Editors and Affiliations

  1. The Tumor Immunology Laboratory, Division of Surgical Oncology, Columbia University, New York, NY

    Howard L. Kaufman

  2. Department of Medicine, Memorial Sloan-Kettering Cancer Center, Weill Medical College of Cornell University, New York, NY

    Jedd D. Wolchok

Rights and permissions

Reprints and permissions

Copyright information

© 2007 Springer

About this chapter

Cite this chapter

Houghton, A.N. (2007). A Perspective on Cancer Immunology and Immunotherapy. In: Kaufman, H.L., Wolchok, J.D. (eds) General Principles of Tumor Immunotherapy. Springer, Dordrecht. https://doi.org/10.1007/978-1-4020-6087-8_1

Download citation

Publish with us

Policies and ethics

Search

Navigation