Overview
- Editors:
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Keith R. Fox
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University of Southampton, UK
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Table of contents (18 protocols)
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- James C. Dabrowiak, Jerry Goodisman, Brian Ward
Pages 23-42
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- Niels Erik Møllegaard, Peter E. Nielsen
Pages 43-49
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- Christian Bailly, Michael J. Waring
Pages 51-79
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- Philip M. Brown, Keith R. Fox
Pages 81-93
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- Suzanne M. Cutts, Andrew Masta, Con Panousis, Peter G. Parsons, Richard A. Sturm, Don R. Phillips
Pages 95-106
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- Suzanne M. Cutts, Con Panousis, Andrew Masta, Don R. Phillips
Pages 107-115
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- Thomas P. Dooley, Katherine L. Weiland
Pages 117-125
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- Don R. Phillips, Carleen Cullinane
Pages 127-145
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- John A. Hartley, Michael D. Wyatt
Pages 147-156
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- Keith A. Grimaldi, John A. Hartley
Pages 157-180
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- Jeremy S. Lee, Laura J. P. Latimer, Jamshid Tanha
Pages 181-188
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- Jeremy S. Lee, Laura J. P. Latimer, Gary D. Burkholder
Pages 189-193
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- W. David Wilson, Farial A. Tanious, Maria Fernandez-Saiz, C. Ted Rigl
Pages 219-240
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Back Matter
Pages 275-278
About this book
In Drug-DNA Interactions, expert researchers describe powerful molecular techniques designed to illuminate and explore the interaction of drugs and ligands with DNA, often perfected in their own laboratories, . These easily reproducible methods involve sequence recognition properties, as well as physical approaches to measuring both the strength of interaction and the mode of drug binding to DNA. Drug interactions are also examined from a cellular perspective and for their usefulness in the development of new therapeutic agents.
Drug-DNA Interactions will be highly useful to all investigators needing the kind of detailed experimental and technical information often omitted from scientific papers. Those wishing to expand their repertoire of experimental techniques or to improve their current techniques will also find these powerful methods particularly helpful in elucidating the action of existing therapeutic agents, as well as in designing new anticancer drugs with improved action and reduced toxicity.
Reviews
"Methods in Molecular Biology is a long standing, respected series that provides protocols for the researcher. ..this particular book is a welcome addition for the researcher. It is recommended for all medical and science libraries."-Reviewer: H. Robert Malinowsky, E-STREAMS
Editors and Affiliations
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University of Southampton, UK
Keith R. Fox