Overview
- Editors:
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Bruce Paul Gaber
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Naval Research Laboratory, USA
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Joel M. Schnur
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Naval Research Laboratory, USA
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Dennis Chapman
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Royal Free Hospital School of Medicine, London, UK
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Table of contents (28 chapters)
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Biophysical Studies of Phospholipid Bilayers
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- Bruce Paul Gaber, Mark Nagumo, William R. Light, Indira Chandrasekhar, Nagarajan Pattabiraman
Pages 1-11
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- Edward M. Arnett, Jeffrey M. Gold, Noel Harvey, Eric A. Johnson, L. Graham Whitesell
Pages 21-36
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- Annette Gulik, Vittorio Luzatti, Mario de Rosa, Agata Gambacorta
Pages 37-45
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- A. Prado, M. S. da Costa, J. Laynez, V. M. C. Madeira
Pages 47-58
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- Jean Luc Ranck, Annette Tardieu, Lucienne Letellier, Emanuel Shechter
Pages 59-69
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Bilayer-Biomolecule Interactions
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- Helmut Hauser, George Strauss
Pages 71-80
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- Félix M. Goñi, Alicia Alonso
Pages 81-103
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- Jan Wilschut, Janny Scholma, Toon Stegmann
Pages 105-126
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- Juan C. Gomez-Fernandez, Francisco J. Aranda, Jose Villalain, Antonio Ortiz
Pages 127-139
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- MarÃa-Angeles Urbaneja, Dennis Chapman
Pages 141-149
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Liposomes as Delivery Systems
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- M. C. Farmer, S. A. Johnson, R. L. Beissinger, J. L. Gossage, A. B. Lynn, K. A. Carter
Pages 161-170
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- Ljubomir Djordjevich, Anthony D. Ivankovich
Pages 171-197
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- J. Szebeni, E. E. Di Iorio, H. Hauser, K. H. Winterhalter
Pages 199-208
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- Bruce P. Gaber, Frances S. Ligler, Reinhard Bredehorst
Pages 209-214
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Artificial Cells
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- David O. Hall, K. Krishna Rao
Pages 225-245
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- Christer Sundqvist, Cecilia Grevby
Pages 247-256
About this book
In the twenty years since Bangham first described the model membrane system which he named "liposomes", a generation of scientists have explored the properties of lipid-based microstructures. Liposomes of all sizes, tubular and helical structures, and self-assembled lipid films have been prepared and studied in detail. Many of the advances· in the basic research have led to significant technological applications. Lipid microstructure research has begun to mature and it is an appropriate time for an in-depth look at the biotechnological applications, both achieved and potential. As a forum for active discussions within this growipg field, two Workshops were organized: "Technological Applications of Phospholipid Bilayers, Vesicles and Thin Films", held in Puerto de la Cruz, Tenerife, Canary Islands; and "Biotechnological Applications of Membrane Studies", held in Donostia-San Sabastian, Basque Country, Spain. The organizers of these Workshops believe that development of lipid self-assembly into a technological discipline requires significant interaction across traditional scientific boundaries. Thus the Workshops gathered an eclectic group of colleagues whose interests ranged from basic research into structure, interactions and stabilization of biomembranes to applications of lipid microstructures such as artificial cells, diagnostic reagents, energy transfer systems, and biosensors.