Overview
- Editors:
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John R. Dean
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Department of Chemical and Life Sciences, University of Northumbria at Newcastle, UK
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Table of contents (8 chapters)
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- S. M. Hitchen, J. R. Dean
Pages 1-11
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- I. D. Wilson, P. Davis, R. J. Ruane
Pages 74-103
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- D. E. Knowles, T. K. Hoge
Pages 104-129
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- V. Janda, K. Bartle, A. A. Clifford
Pages 159-187
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Back Matter
Pages 219-224
About this book
The continued search for rapid, efficient and cost-effective means of analytical measurement has introduced supercritical fluids into the field of analytical chemistry. Two areas are common: supercritical fluid chroma tography and supercritical fluid extraction. Both seek to exploit the unique properties of a gas at temperatures and pressures above the critical point. The most common supercritical fluid is carbon dioxide, employed because of its low critical temperature (31 °C), inertness, purity, non-toxicity and cheapness. Alternative supercritical fluids are also used and often in conjunction with modifiers. The combined gas-like mass transfer and liquid-like solvating characteristics have been used for improved chroma tographic separation and faster sample preparation. Supercritical fluid chromatography (SFC) is complementary to gas chro matography ( GC) and high performance liquid chromatography (HPLC), providing higher efficiency than HPLC, together with the ability to analyse thermally labile and high molecular weight analytes. Both packed and open tubular columns can be employed, providing the capability to analyse a wide range of sample types. In addition, flame ionization detection can be used, thus providing 'universal' detection.
Reviews
...well organized and edited and can be recommended to those who want to apply SFC/SFE in their work. - Trends in Analytical Chemistry.; In conclusion, the book makes a useful contribution in transfering supercritical fluid methods from a basic study area to an application that solves real problems. - Chemistry in Britain
Editors and Affiliations
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Department of Chemical and Life Sciences, University of Northumbria at Newcastle, UK
John R. Dean
