Hypoparathyroidism

  • Maria Luisa Brandi
  • Edward Meigs Brown

Table of contents

  1. Front Matter
    Pages i-xvii
  2. Anatomy and Physiology of the Parathyroid Glands

    1. Front Matter
      Pages 1-1
    2. Michael Mannstadt, John T. Potts Jr.
      Pages 3-10
    3. Nancy R. Manley
      Pages 11-18
    4. Giancarlo Isaia, Margherita Marchetti
      Pages 19-24
    5. Pierre D’Amour
      Pages 25-32
    6. Piergiorgio Messa
      Pages 49-59
    7. Oren Steen, Aliya Khan
      Pages 61-67
    8. David Goltzman, Andrew C. Karaplis
      Pages 69-79
    9. Thomas J. Gardella
      Pages 81-87
    10. Murat Bastepe
      Pages 89-98
    11. Paola Divieti Pajevic, Marc N. Wein, Henry M. Kronenberg
      Pages 99-109
    12. Luisella Cianferotti
      Pages 111-126
    13. Ana Rita Gomez, Sergio Fabbri, Maria Luisa Brandi
      Pages 127-135
  3. Conditions of Hypoparathyroidism

    1. Front Matter
      Pages 137-137
    2. Bart L. Clarke
      Pages 139-154
    3. Amber L. Wheeler, Dolores M. Shoback
      Pages 155-165
    4. Geoffrey N. Hendy, David E. C. Cole
      Pages 167-175
    5. E. Helen Kemp, Anthony P. Weetman
      Pages 177-188

About this book

Introduction

Hypoparathyroidism, a condition in which insufficient parathyroid hormone (PTH) is produced to maintain normocalcemia is associated with a variety of acute and chronic symptoms and complications due to hypocalcemia. Replacement therapy utilizing PTH has long been awaited, and this book is new and very timely as it coincides with the  publication of results on the role of the PTH molecule in the pharmacological management of this disorder. This advance is sparking renewed interest in hypoparathyroidism, which is attributable to neck surgery in most cases and to inherited disorders in a minority.

Hypoparathyroidism has been written by acknowledged experts in the field and provides essential, up-to-date information on the pathology, diagnosis, and treatment of the condition. It opens by addressing in detail the anatomy and physiology of the parathyroids and describing the epidemiology and clinical presentation of hypoparathyroidism. The full range of hypoparathyroid disorders are then discussed, including the various genetic forms, postoperative hypoparathyroidism, and other forms of acquired hypoparathyroidism. Individual chapters focus on refractory disease, the impact of the condition on bone, and the management of acute hypocalcemia. Both conventional treatment for hypoparathyroidism and the novel replacement therapy with PTH  peptides are then thoroughly examined. Pseudohypoparathyroidism is also extensively discussed, with information on the various forms, differential diagnosis, and genetic testing. This book will be of interest to all endocrinologists, and also to surgeons and internal medicine physicians.

 

Keywords

Hypoparathyroidism Parathyroid hormone Parathyroid physiology Parathyroid surgery Parathyroids

Editors and affiliations

  • Maria Luisa Brandi
    • 1
  • Edward Meigs Brown
    • 2
  1. 1.Unit of Metabolic and Bone DiseasesUniversity of FlorenceFlorenceItaly
  2. 2.Division of Endocrinology, Diabetes and HypertensionHarvard Medical School and Brigham & Women's HospitalBostonUSA

Bibliographic information

  • DOI https://doi.org/10.1007/978-88-470-5376-2
  • Copyright Information Springer-Verlag Italia 2015
  • Publisher Name Springer, Milano
  • eBook Packages Medicine
  • Print ISBN 978-88-470-5375-5
  • Online ISBN 978-88-470-5376-2
  • About this book
Industry Sectors
Biotechnology
Pharma