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Effects of Mineral Dusts on Cells

  • Conference proceedings
  • © 1989

Overview

Editors:
  1. Brooke T. Mossman

    1. College of Medicine Department of Pathology, University of Vermont, Burlington, USA

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    You can also search for this editor in PubMed   Google Scholar

  2. Raymond O. Bégin

    1. Service de Pneumologie, CHUS, Sherbrooke, Canada

    View editor publications

    You can also search for this editor in PubMed   Google Scholar

Part of the book series: Nato ASI Subseries H: (ASIH, volume 30)

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Table of contents (58 papers)

  1. Front Matter

    Pages I-XII
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  3. Physico-Chemical Properties of Minerals in Relation to their Biologic Effects

    1. Toxicity of Chrysotile Asbestos through Surface Modification with Chelating Agents

      • M. Martin, M. Pagé, F. Habashi, F. T. Awadalla
      Pages 23-25

    2. A Comparison of the In Vivo and In Vitro Toxicity of Fibrous and Non-Fibrous Silicon Nitride

      • G. L. Fisher, K. L. McNeill, A. W. Singer, J. T. Smith
      Pages 27-35

    3. Membranolytic Activity and Morphological Characterization of Palygorskite and Sepiolite

      • R. P. Nolan, A. M. Langer, G. B. Herson
      Pages 37-48

    4. Mineral Surface-Specific Differences in the Adsorption and Enzymatic Removal of Surfactant and Their Correlation with Cytotoxicity

      • W. E. Wallace, M. J. Keane, P. S. Mike, C. A. Hill, V. Vallyathan
      Pages 49-56

  4. Mechanisms of Dust-Induced Pneumoconioses. Clinical and Experimental Studies

    1. Bronchoalveolar Lavage Cells in Occupational Exposure to Mineral Fibers

      • A. Forni, G. Rivolta, G. Chiappino
      Pages 57-64

    2. Alveolar Macrophages Secretory Dysfunctions in Coal Workers’s Pneumoconiosis. Comparison Between Simple Pneumoconiosis and Progressive Massive Fibrosis.

      • P. Lassalle, P. Gosset, C. Aerts, M. Benhamou, F. Fortin, B. Wallaert et al.
      Pages 65-71

    3. Cellularity in Bronchoalveolar Lavage in Cement Dust Aggression

      • A. J. A. Robalo-Cordeiro, M. F. Baganha, M. Melo, J. R. G. Almeida, L. Chieira, I. Mesquita et al.
      Pages 73-79

    4. Carborundum Pneumoconiosis

      • R. Bégin, A. Dufresne, A. Cantin, S. Massé, P. Sébastien, P. Durand et al.
      Pages 81-84

  5. Mechanisms of Cytotoxicity, Mutagenicity and Carcinogenicity

    1. Influence of Physicochemical Properties of Beryllium and Nickel Compounds on Cultured Cell Toxicity

      • G. L. Finch, A. L. Brooks, J. M. Benson, M. D. Hoover, J. A. Mewhinney, A. F. Eidson et al.
      Pages 85-92

    2. Comparative Study of the Effect of Various Fibres on the Secretion of Plasminogen Activator by Murine Peritoneal Macrophages

      • D. Godelaine, H. Beaufay
      Pages 93-100

    3. Release of lnterleukin-1 and Tumor Necrosis Factor by Rat Alveolar Macrophages after In Vivo or In Vitro Exposure to Mineral Dusts

      • K. E. Driscoll, R. C. Lindenschmidt, J. K. Maurer, J. M. Higgins
      Pages 101-108

    4. The Effect of Aramid and Metaphosphate Fibers on Macrophage Viability and Function

      • Candace S. Wheeler, Charles D. Garner
      Pages 109-114

    5. Effects of Nicotinamide on the Cytotoxicity of Mineral Dusts Towards Pulmonary Alveolar Macrophages

      • D. Nadeau, D. A. Lane, D. Paradis, L. Fouquette
      Pages 115-122

    6. Long-Term Effect of 3Methylcholanthrene-Coated Asbestos Fibres on the Immune Status of F1(NZB*C57B1/6) Mice

      • A. Lange, B. Pietrzyca, A. Moniewska, J. Rabczynski
      Pages 123-131

    7. Production of Growth Factors by Rat Pleural Mesothelial Cells In Vivo or In Vitro Transformed by Chrysotile Fibers

      • A. Van der Meeren, G. Clement, J. Bignon, D. Barritault, M. C. Jaurand
      Pages 133-140

    8. Mutagenicity of Asbestos and Erionite in a Salmonella Tester Strain of TA102

      • Eiji Yano, Makoto Shimizu, Naoko Urano, Peter H. Evans
      Pages 141-148
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Keywords

About this book

The Fourth International Workshop on "In Vitro Effects of Mineral Dusts on Cells" was held on September 20 - 23, 1988 in Auberge Estrimont, Orford, Quebec, Canada. The emphasis of the N. A. T. O. Advanced Research Workshop was the use of cell and organ culture and lavage cell populations obtained from man and laboratory animals to elucidate cellular and molecular events occur­ ring after their interaction with fibrous and nonfibrous particulates, including metal compounds. In seven sessions, an international representation of scientists from 17 countries (Austria, Belgium, Canada, France, Federal Republic of Germany, India, Japan, Netherlands, Norway, Poland, Portugal, Union of South Africa, Sweden, Switzerland, United Kingdom, United States of America, and Yugoslavia) presented recent research findings in the following areas: Epithelial cell injury and proliferation by minerals. Physico-chemical properties of minerals in relation to their biologic effects. Mechanisms of dust-induced pneumoconioses. Clinical and experimental studies. Mechanisms of cytotoxicity, mutagenicity and carcinogenicity. Oxidants, cytotoxicity and disease. Mechanisms of mineral-induced inflammation. Mechanisms of carcinogenesis. A session on "Questions, risk and public policy" provided a lively discussion on the relevance of in vitro experiments to carcinogenicity studies in man and their implications in the formation of regulatory policies. VI The organizing committee for this workshop was: Co-Chairs: B. T. Mossman (USA) and R. Begin (Canada) E. G. Beck (FRG) A. Lange (Poland) A. Brody (USA) P. Nettesheim (USA) R. C. Brown (UK) Q. Rahman (India) J. Bignon (France) K. Robock (FRG) Fisher G.

Editors and Affiliations

  • College of Medicine Department of Pathology, University of Vermont, Burlington, USA

    Brooke T. Mossman

  • Service de Pneumologie, CHUS, Sherbrooke, Canada

    Raymond O. Bégin

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