Production of Growth Factors by Rat Pleural Mesothelial Cells In Vivo or In Vitro Transformed by Chrysotile Fibers

  • A. Van der Meeren
  • G. Clement
  • J. Bignon
  • D. Barritault
  • M. C. Jaurand
Part of the NATO ASI Series book series (volume 30)

Abstract

Mesothelial cells are target cells in asbestos-related carcinogenesis. Chrysotile fibers are known to induce mesothelioma in vivo (Wagner et al. 1969; Monchaux et al. 1981) and mesothelial cell transformation in vitro (Paterour et al. 1985).

Keywords

Dust Heparin Penicillin Retina Polypeptide 

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References

  1. Antoniades HN, Scher CD, and Stiles CD (1979) Purification of human platelet derived growth factor. Proc Natl Acad Sci USA 76: 1809–1813PubMedCrossRefGoogle Scholar
  2. Bradshaw TK (1986) Cell transformation: the role of oncogenes and growth factors. Mutagenesis 1: 91–97PubMedCrossRefGoogle Scholar
  3. Burgess W, Mehlman T, Friesel R, Johnson W and Maciag T (1985) Multiple forms of endothelial cell growth factor. J Biol Chem 260: 11389–11392PubMedGoogle Scholar
  4. Clemmons D (1983) Age dependent production of a competence factor by human fibroblasts. J Cell Physiol 114: 61–67PubMedCrossRefGoogle Scholar
  5. Courty J, Chevallier B, Moenner M, Loret C, Lagerte O, Bohlen P, Courtois Y, Barritault D (1986) Evidence for FGF-like growth factor in adult bovine retina: analogies with EDGF-1. Biochem Biophys Res Comm 136: 102–108PubMedCrossRefGoogle Scholar
  6. Gabrielson EW, Gerwin BI, Harris CC, Roberts AB, Sporn MB and Lechner JF (1988) Stimulation of DNA synthesis in cultured primary human mesothelial cells by specific growth factors. FASEB J 2: 2717–2721PubMedGoogle Scholar
  7. Gerwin BI, Lechner JF, Reddel RR, Roberts AB, Robbins KC, Gabrielson EW and Harris CC (1987) Comparison of production of transforming growth factor ß and platelet derived growth factor by normal human mesothelial cells and mesothelioma cell lines. Cancer Res 47: 6180–6184PubMedGoogle Scholar
  8. Jaurand MC, Bernaudin JF, Renier A, Kaplan H, Bignon J (1981) Rat pleural mesothelial cells in culture. In Vitro 17: 98–108Google Scholar
  9. Jaurand MC, Renier A, Van der Meeren A, Magne L, Pinchon MC and Bignon J (1986) In vitro growth characteristics of rat mesothelioma cells in culture. Biol Cell 57: 249–256PubMedGoogle Scholar
  10. Klagsborn M and Shirg Y (1985) Heparin affinity of anionic and cationic capillary endothelial cell growth factors: analysis of hypothalamus derived growth factors and fibroblast growth factors. Proc Natl Acad Sci USA 82: 805- 809Google Scholar
  11. La Rocca P and Rheinwald JG (1985) Anchorage independent growth of normal human mesothelial cells: a sensitive bioassay for EGF which discloses the absence of this factor in fetal calf serum. In Vitro Cellular et Dev Biol 21: 67–72Google Scholar
  12. Lens PF, Altera B, Nuser (1986) Expression of c-sis and platelet-derived growth factor in in vitro transformed glioma cells from rat brain tissue transplacental treated with ethylnitrosourea. Mol and Cell Biol 6: 3537–3540Google Scholar
  13. Levy F, Van der Meeren A, Renier A, Katz A, Bignon J and Jaurand MC. (1988) First studies on cell cycles of rat pleural mesothelial cells submitted to direct and indirect hit by chrysotile fibres. 4th Int Workshop on Effects of Mineral Dusts on Cells, Sherbrooke, Canada 21–23 SeptGoogle Scholar
  14. Monchaux G, Bignon J, Jaurand MC, Lafuma J, Sebastien P, Masse R, Hirsch A and Goni J (1981) Mesotheliomas in rats following inoculation with acid-leached chrysotile asbestos and other mineral fibres. Carcinog 2: 229–236CrossRefGoogle Scholar
  15. Paterour MJ, Bignon J and Jaurand MC (1985) In vitro transformation of rat pleural mesothelial cells by chrysotile fibres and/or benzo(a) pyrene. Carcinog 6: 523–529CrossRefGoogle Scholar
  16. Saint-Etienne L, Paterour MJ, Nebut M, Fleury J, Kheuang L, Bignon J and Jaurand MC (1988) Occurence and morphology of tumors induced in nude mice transplanted with pleural mesothelial cells in vitro treated with chrysotile fibres or benzo 3-4 pyrene. 4th Int Workshop on Effects of Mineral Dusts on Cells, Sherbrooke, Canada 21–23 SeptGoogle Scholar
  17. Schreiber A, Kenny S, Kowalski J, Thomas K, Gimenez-Galleco G, Los Candelarc M, Di Salvo J, Barritault D, Courty J, Courtois Y, Moenner M, Loret C, Burges W, Mehlman T, Firesel R, Johnsson W and Maciag J (1985) A unique family of endothelial cell polypeptide mitogens: the antigenic and receptor cross reactivity of bovine endothelial cell growth factor, brain derived acidic fibroblast growth factor and eye derived growth factor II. J Cell Biol 101: 1623–1626PubMedCrossRefGoogle Scholar
  18. Sporn MB and Todaro GJ (1980) Autocrine secretion and malignant transformation of cells. New Engl J Med 303: 878–880PubMedCrossRefGoogle Scholar
  19. Van der Meeren A, Levy F, Bignon J and Jaurand MC (1988) Growth of normal and neoplastic rat pleural mesothelial cells in the presence of conditioned medium from neoplastic mesothelial cells. Biol Cell 62: 293–296PubMedCrossRefGoogle Scholar
  20. Wagner JC and Berry G (1969) Mesotheliomas in rats following inoculation with asbestos. Brit J Cancer 23: 567–581PubMedCrossRefGoogle Scholar

Copyright information

© Springer-Verlag Berlin Heidelberg 1989

Authors and Affiliations

  • A. Van der Meeren
    • 1
  • G. Clement
    • 2
  • J. Bignon
    • 1
  • D. Barritault
    • 2
  • M. C. Jaurand
    • 1
  1. 1.CHU Henri-MondorINSERM U 139Créteil CedexFrance
  2. 2.Laboratoire de Biotechnologie des Cellules EucaryotesUniversité Paris-Val de MarneCréteil CedexFrance

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