Membranolytic Activity and Morphological Characterization of Palygorskite and Sepiolite

  • R. P. Nolan
  • A. M. Langer
  • G. B. Herson
Conference paper
Part of the NATO ASI Series book series (volume 30)


The hormitic clays, palygorskite (attapulgite) and sepiolite, are being commercially used for many different applications. In 1983, approximately 1.1 million tons of palygorskite was used in industrial countries of the western world, as compared to 400,000 tons of sepiolite in 1984 (see IARC, 1987, for production, consumption, and application data). Concern about the potential health hazard of these minerals has arisen due to their fibrous nature and extensive application as asbestos substitutes (Bignon et al, 1980).


Mount Sinai School Potential Health Hazard Chrysotile Asbestos Mineral Fiber Mineral Specimen 
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  1. Bignon J, Sebastien P, Gaudichet A, Jaurand MC (1980) Biological Effects of Attapulgite. In: Wagner JC (ed) Biological Effects of Mineral Fiber, Vol. 1. IARC Scientific Publication No. 30, Lyon, France, p. 163.Google Scholar
  2. Chamberlain M, Davis R, Brown RC, Griffiths DM (1982) In vitro tests for the pathogenicity of mineral dusts. Ann Occup Hyg 26: 583–592.PubMedCrossRefGoogle Scholar
  3. Harvey G, Page M, Dumas L (1984) Binding of environmental carcinogens to asbestos and mineral fibers. Br J Ind Med 41: 396–400.PubMedGoogle Scholar
  4. IARC (1987) Silica and silicates. Monographs on the evaluation of carcinogenic risk of chemicals to health. IARC Scientific Publication No. 40, Lyon, France, pp. 159–173, pp. 175–183.Google Scholar
  5. Langer AM, Wolff MS, Rohl AN, Selikoff IJ (1978) Variation of properties of chrysotile asbestos, subjected to prolonged milling. J Toxicol Environ Sci 4: 173–188.Google Scholar
  6. Nolan RP, Langer AM, Harington JS, Oster G, Selikoff IJ (1981). Quartz hemolysis as related to its surface functionalities. Environ Res 26: 503–520.PubMedCrossRefGoogle Scholar
  7. Pott F, Ziem U, Reiffer FJ, Huth F, Ernst H, Mohr U (1987). Carcinogenicity studies on fibers, metal compounds and some other dusts in rats. Exper Path 32: 129–152.CrossRefGoogle Scholar
  8. Wagner JC, Griffiths DM, Munday DE (1987) Experimental studies with palygorskite dusts. Br J Ind Med 44: 749–763.PubMedGoogle Scholar

Copyright information

© Springer-Verlag Berlin Heidelberg 1989

Authors and Affiliations

  • R. P. Nolan
    • 1
  • A. M. Langer
    • 1
  • G. B. Herson
    • 2
  1. 1.Environmental Sciences LaboratoryApplied Sciences Institute of The City University of New York At Brooklyn CollegeBrooklynUSA
  2. 2.Andre Meyer Department of Physics and Nuclear MedicineMount Sinai School of MedicineNew YorkUSA

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