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Antiviral Drug Development

A Multidisciplinary Approach

  • Conference proceedings
  • © 1988

Overview

Editors:
  1. Erik Clercq

    1. Katholieke Universiteit Leuven, Leuven, Belgium

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  2. Richard T. Walker

    1. The University of Birmingham, Birmingham, UK

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    You can also search for this editor in PubMed   Google Scholar

Part of the book series: NATO Science Series A: (NSSA, volume 143)

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Table of contents (16 papers)

  1. Front Matter

    Pages i-viii
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  2. Antiviral Chemotherapy: An Introduction and Reasons for the Slow Progress, Particularly towards Rational Design

    • Richard T. Walker
    Pages 1-9

  3. Design of Nucleoside Analogs as Potential Antiviral Agents

    • Roland K. Robins, Ganapathi R. Revankar
    Pages 11-36

  4. Design of Anti-Viral Agents Other than Nucleoside Analogues

    • Stanley M. Roberts
    Pages 37-54

  5. Antivirals for High Hazard Viruses

    • Peter G. Canonico
    Pages 55-72

  6. Human Retroviruses and Anti-Viral Therapies

    • R. C. Gallo, M. S. Reitz Jr.
    Pages 73-80

  7. Epstein-Barr Virus

    • Joseph S. Pagano
    Pages 81-96

  8. Molecular Targets for Selective Antiviral Chemotherapy

    • Erik De Clercq
    Pages 97-122

  9. Inhibition of S-Adenosylmethionine-Dependent Transmethylation as an Approach to the Development of Antiviral Agents

    • Bradley T. Keller, Ronald T. Borchardt
    Pages 123-138

  10. Assay Systems: Testing of Antiviral Drugs in Cell Culture (In Vitro)

    • Hans J. Eggers
    Pages 139-148

  11. Animal Models as Assay Systems for the Development of Antivirals

    • Earl R. Kern
    Pages 149-172

  12. Experimental Aspects of Antiviral Pharmacology

    • William H. Prusoff, Tai-Shun Lin
    Pages 173-202

  13. Virus Drug Resistance

    • Hugh J. Field, Lindsey J. Owen
    Pages 203-236

  14. Interferon as an Antiviral Agent

    • H. Schellekens
    Pages 237-249

  15. Risk-Benefit Analysis in Drug Research

    • Paul Janssen
    Pages 251-259

  16. Safety Assessment of Antiviral Drugs

    • Elaine C. Esber, Robert C. Nelson, Norma Jean Browder
    Pages 261-273

  17. Antiviral Agents: A New Beginning

    • George J. Galasso
    Pages 275-298

  18. Back Matter

    Pages 299-309
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Keywords

Editors and Affiliations

  • Katholieke Universiteit Leuven, Leuven, Belgium

    Erik Clercq

  • The University of Birmingham, Birmingham, UK

    Richard T. Walker

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