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Human Retroviruses and Anti-Viral Therapies

  • Conference paper
Antiviral Drug Development

Part of the book series: NATO ASI Series ((NSSA,volume 143))

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Abstract

At least four types of human retroviruses are currently identified. They are causally involved in several different kinds of diseases in humans, including leukemia and lymphoma immunodeficiency diseases and neurologic and central nervous system diseases. Their identification has led to the ability to easily detect them and to a basic understanding of their life cycle. This knowledge makes possible various strategies for prevention and treatment of diseases due to infection by these viruses.

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References

  1. B.J. Poiesz, F.W. Ruscetti, A.F. Gazdar, P.A. Bunn, J.D. Minna, and R.C. Gallo, Detection and isolation of type C retrovirus particles from fresh and cultured lymphocytes of a patient with cutaneous T-cell lymphoma, Proc. Natl. Acad. Sci USA 77:7415 (1980).

    Article  PubMed  CAS  Google Scholar 

  2. V.S. Kalyanaraman, M.G. Sarngadharan, M. Robert-Guroff, I. Miyoshi, D. Blayney, D. Golde, and R.C. Gallo, A new subtype of human T-cell leukemia virus (HTLV-II) associated with a T-cell variant of hairy cell leukemia, Science 218:571 (1982).

    Article  PubMed  CAS  Google Scholar 

  3. R.C. Gallo, S.Z. Salahuddin, M. Popovic, G.M. Shearer, M. Kaplan, B.F. Haynes, T.J. Palker, R. Redfield, J. Oleste, B. Safai, G. White, P. Foster, and P.D. Markham, Frequent detection and isolation of cyto-pathic retroviruses (HTLV-III) from patients with AIDS and at risk for AIDS, Science 224:500 (1984).

    Article  PubMed  CAS  Google Scholar 

  4. F. Barré-Sinoussi, J.C. Chermann, F. Rey, M.T. Nugeybe, S. Chamaret, J. Gruest, C. Dauguet, C. Axler-Blin, F. Brun-Vezinet, C. Rou-zioux, W. Rozenbaum, and L. Montagnier, Isolation of a T-lymphotropic retrovirus from a patient as risk of acquired immune deficiency syndrome (AIDS), Science 220:868 (1983).

    Article  PubMed  Google Scholar 

  5. P.J. Kanki, J. Alroy, and M. Essex, Isolation of T-lymphotropic retrovirus related to HTLV-III/LAV from wild-caught African green monkeys, Science 230:951 (1985).

    Article  PubMed  CAS  Google Scholar 

  6. F. Clavel, D. Guetard, F. Brun-Vezinet, S. Chamaret, M.A. Rey, M.O. Santos-Ferreira, A.G. Laurent, C. Dauguet, C. Katlama, C. Rouzioux, D. Klatzmann, S.L. Champalimand, and L. Montagnier, Isolation of a new human retrovirus from West African patients with AIDS, Science 233:343 (1986).

    Article  PubMed  CAS  Google Scholar 

  7. P.J. Kanki, F. Barin, S. M’Boup, J.S. Allan, J.L. Romet-Lemonne, R. Markink, M.F. McLane, T.H. Lee, B. Arbeille, and M. Essex, New human T-lymphotropic retrovirus related to simian T-lymphotropic virus type III (STLV-III), Science 232:238 (1986).

    Article  PubMed  CAS  Google Scholar 

  8. F. Wong-Staal and R.C. Gallo, Human T-lymphotropic retroviruses, Nature 317:395 (1985).

    Article  PubMed  CAS  Google Scholar 

  9. H. Mitsuya and S. Broder, Strategies for antiviral therapy in AIDS, Nature 325:773 (1987).

    Article  PubMed  CAS  Google Scholar 

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© 1988 Plenum Press, New York

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Gallo, R.C., Reitz, M.S. (1988). Human Retroviruses and Anti-Viral Therapies. In: De Clercq, E., Walker, R.T. (eds) Antiviral Drug Development. NATO ASI Series, vol 143. Springer, Boston, MA. https://doi.org/10.1007/978-1-4684-7275-2_5

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  • DOI: https://doi.org/10.1007/978-1-4684-7275-2_5

  • Publisher Name: Springer, Boston, MA

  • Print ISBN: 978-1-4684-7277-6

  • Online ISBN: 978-1-4684-7275-2

  • eBook Packages: Springer Book Archive

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