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Targeting of Drugs 5

Strategies for Oligonucleotide and Gene Delivery in Therapy

  • Book
  • © 1996

Overview

Editors:
  1. Gregory Gregoriadis

    1. School of Pharmacy, University of London, London, England

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    You can also search for this editor in PubMed   Google Scholar

  2. Brenda McCormack

    1. School of Pharmacy, University of London, London, England

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    You can also search for this editor in PubMed   Google Scholar

Part of the book series: NATO Science Series A: (NSSA, volume 290)

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Table of contents (19 chapters)

  1. Front Matter

    Pages i-viii
    Download chapter PDF

  2. Gene Therapy for Inherited Genetic Disease: Possibilities and Problems

    • Charles Coutelle
    Pages 1-13

  3. Gene Delivery and Therapy: The Case for Cystic Fibrosis

    • Eric W F W Alton
    Pages 15-19

  4. Immune Responses with Direct Gene Transfer: DNA Vaccines and Implications for Gene Therapy

    • Heather L. Davis
    Pages 21-29

  5. Oligonucleotides: Molecular Versions for Optimal use in Vivo

    • E. Saison-Behmoaras, A. Van Aerschot, I. Duroux, C. Hendrix, C. Hélène, P. Herdewijn
    Pages 31-43

  6. Retrovirus Vectors in Gene Therapy: Targeting to Specific Cells

    • A. J. Kingsman, Y. Bae, J. C. Griffiths, N. Kim, E. E. Ramsdale, G. Romano et al.
    Pages 45-51

  7. Adenovirus as Vectors for Gene Therapy

    • Martin G Lee
    Pages 53-65

  8. Receptor-Mediated Gene Delivery with Synthetic Virus-Like Particles

    • Ernst Wagner, Matt Cotten, Kurt Zatloukal
    Pages 67-77

  9. Controllable Gene Therapy: Recent Advances in Non-Viral Gene Delivery

    • Alain Rolland
    Pages 79-95

  10. Genetic Chemistry: Towards Non-Enzymatic Ligation, Sequence-Selective Recognition of DNA, and Self-Assembling Systems for Gene Delivery

    • Jean-Paul Behr
    Pages 97-100

  11. Integrin-Mediated Gene Delivery

    • Stephen L. Hart, Richard P. Harbottle, Charles Coutelle
    Pages 101-106

  12. Design, Synthesis, and Cellular Delivery of Antibody Targeted, Radiolabelled Oligonucleotide Conjugates for Cancer Therapy

    • C S R Gooden, A A Epenetos
    Pages 107-114

  13. Poly (L Lysine) Mediated Delivery of Nucleic Acids

    • B. Lebleu, L. Bastide, C. Bisbal, J. P. Bongartz, G. Degols, J. P. Leonetti et al.
    Pages 115-123

  14. Complement Activation by Polylysine-DNA Complexes

    • C. Plank, K. Mechtler, E. Wagner, F. C. Szoka Jr.
    Pages 125-130

  15. Nanoparticles as Carriers for Antisense Oligonucleotides

    • Olivier Balland, Tula Saison-Behmoaras, Thérèse Garestier, Claude Hélène
    Pages 131-142

  16. Efficient Incorporation of Plasmid DNA Within Liposomes of Varying Structural Characteristics: Liposomal DNA Integrity and Transfection Efficiency

    • Gregory Gregoriadis, Roghieh Saffie, Stephen L. Hart
    Pages 143-150

  17. pH Sensitive Liposomes as Efficient Carriers for Intracellular Delivery of Oligonucleotides

    • C. Ropert, C. Malvy, P. Couvreur
    Pages 151-162

  18. Liposomal Delivery of P-Ethoxy Antisense Oligodeoxynucleotides in Chronic Myelogenous Leukemia

    • A. M. Tari, N. Neamati, M. Andreeff, G. Lopez-Berestein
    Pages 163-168

  19. Liposome-Mediated Delivery of Genes and Oligonucleotides for the Treatment of Brain Tumors

    • Jianhong Zhu, Li Zhang, Regina Reszka
    Pages 169-178

  20. Enzyme Assisted Synthesis of Delivery Systems

    • M. Berger, B. Jakob, C. Waldinger, M. P. Schneider
    Pages 179-191
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Keywords

Editors and Affiliations

  • School of Pharmacy, University of London, London, England

    Gregory Gregoriadis, Brenda McCormack

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