Abstract
The concept of “complementary addressed oligonucleotides” as a tool to control specifically gene expression has been initially formulated by the group of Knorre and Vlassov as review in (1985). A first demonstration of a possible control of Rous sarcoma virus gene expression by synthetic oligonucleotides has been provided by Zamecnik and Stephenson (1978).
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Lebleu, B. et al. (1996). Poly (L Lysine) Mediated Delivery of Nucleic Acids. In: Gregoriadis, G., McCormack, B. (eds) Targeting of Drugs 5. NATO ASI Series, vol 290. Springer, Boston, MA. https://doi.org/10.1007/978-1-4615-6405-8_12
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DOI: https://doi.org/10.1007/978-1-4615-6405-8_12
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