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Thrombolytic Therapy in Acute Ischemic Stroke III

  • Conference proceedings
  • © 1995

Overview

Editors:
  1. Takenori Yamaguchi

    1. Cerebrovascular Division, Department of Internal Medicine, National Cardiovascular Center, Suita, Osaka, 565, Japan

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  2. Etsuro Mori

    1. Clinical Neurosciences, Hyogo Institute for Aging Brain and Cognitive Disorders, Himeji, Hyogo, 670, Japan

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  3. Kazuo Minematsu

    1. Cerebrovascular Division, Department of Internal Medicine, National Cardiovascular Center, Suita, Osaka, 565, Japan

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  4. Gregory J. Zoppo

    1. Department of Molecular and Experimental Medicine, The Scripps Research Institute and Division of Hematology/Medical Oncology, Scripps Clinic and Research Foundation, La Jolla, USA

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Table of contents (42 papers)

  2. Future in Thrombolytic Therapy: New Thrombolytic Agents and Combination Therapies

    1. Front Matter

      Pages 163-163
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    2. Thrombolytic Therapy in Acute Ischemic Stroke: Combination Therapy with Antiplatelet and Anticoagulant Agents

      • N. G. Wahlgren
      Pages 165-173

    3. Combination Therapy with Cytoprotective Agents

      • K. Minematsu
      Pages 174-181

    4. New Thrombolytic Agents: Basic Development

      • O. Matsuo
      Pages 182-187

  3. Results and Progress in Clinical Trials of Thrombolytic Therapy

    1. Front Matter

      Pages 191-191
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    2. The NINDS t-PA Stroke Trial: Progress Report

      • The NINDS t-PA Stroke Trial Investigators
      Pages 193-197

    3. Is Thrombolysis Useful for Acute Stroke Patients? The Experience of the MAST-I Study

      • The MAST-I Collaborative Group
      Pages 198-205

    4. The Multicenter Acute Stroke Trial (MAST)—Thrombolysis Study: Study Design and Progress Report

      • The MAST Group
      Pages 206-213

    5. Australian Streptokinase Trial: Progress Report

      • G. A. Dorman, S. M. Davis, B. R. Chambers, P. Gates, E. Stewart-Wynne, D. Rosen et al.
      Pages 214-217

    6. European Cooperative Acute Stroke Study: Trial Protocol

      • C. Argentino, W. Hacke, M. Kaste, C. Fieschi, ECASS Study Group
      Pages 218-222

    7. Clinical Efficacy and Safety of Intravenous Tissue Plasminogen Activator in Acute Embolic Stroke: A Randomized, Double-Blind, Dose-Comparison Study of Duteplase

      • T. Yamaguchi, H. Kikuchi, T. Hayakawa, for the Japanese Thrombolysis Study Group
      Pages 223-229

  4. Unresolved Problems

    1. Front Matter

      Pages 233-233
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    2. Recanalization and Hemorrhage

      1. Delayed Recanalization and Reocclusion Following Thrombolysis for Acute Stroke
        • A. J. Furlan
        Pages 235-241
      2. Intracranial Hemorrhage in Association with Thrombolysis: Multiple Causes and Risk Factors (No Simple Answer)
        • M. S. Pessin, G. J. del Zoppo
        Pages 242-253
      3. Mechanisms of Fibrinolysis-Associated Hemorrhagic Transformation
        • G. J. del Zoppo, Y. Okada, G. F. Hamann, R. Fitridge, M. S. Pessin
        Pages 254-266

  5. Unresolved Problems

    1. Front Matter

      Pages 233-233
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    2. Which Route is Best?

      1. Plasminogen Plus rt-PA Improves Intraarterial Thrombolytic Therapy in Acute Ischemic Stroke
        • H.-J. Freitag, V. Becker, A. Thie, V. Tilsner, A. Philapitsch, H. P. Schwarz et al.
        Pages 271-278
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Keywords

About this book

On the threshold of an exciting new era for acute stroke diagnosis and treatment, the Third International Symposium on Thrombolytic Therapy in Acute Ischemic Stroke was held in Nara, Japan, in April 1994. The symposium brought together some 200 basic and clinical scientists for presentations and discussions of issues vital to the understanding of thrombolytic therapy. This volume compiles the major presentations of the symposium, with attention to applications of new diagnostic measures such as diffusion and perfusion MRI, contrast-enhanced transcranial Doppler and angioscopy. Other presentations examine the mechanisms of ischemia/reperfusion injury, hemorrhagic transformation, and reocclusion, with reviews of recent developments in thrombolytic agents. The proceedings of the symposium will be of special interest to researchers, physicians, and students in the fields of neurology, neurosurgery, and nuclear medicine, as well as those in pharmacology, critical care medicine, and related fields.

Editors and Affiliations

  • Cerebrovascular Division, Department of Internal Medicine, National Cardiovascular Center, Suita, Osaka, 565, Japan

    Takenori Yamaguchi, Kazuo Minematsu

  • Clinical Neurosciences, Hyogo Institute for Aging Brain and Cognitive Disorders, Himeji, Hyogo, 670, Japan

    Etsuro Mori

  • Department of Molecular and Experimental Medicine, The Scripps Research Institute and Division of Hematology/Medical Oncology, Scripps Clinic and Research Foundation, La Jolla, USA

    Gregory J. Zoppo

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