Abstract
Experimental and physiopathological studies suggest that reperfusion may be useful to prevent the extension of brain infarction if performed in a reasonable period of time after ischemic insult. Thrombolytic agents recanalize myocardial and cerebral vessels, but it is not yet known if they are able to reperfuse brain ischemic tissue. There is some experimental evidence in animals of their efficacy, but it is still uncertain if these agents are able to reduce the size of brain infarct and improve clinical outcome in man.
The members are listed in the Appendix and correspondence should be addressed to: Livia Candelise, Instituto di Clinica Nerologica, Via F. Sforza 35. 20122 Milan, Italy
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© 1995 Springer-Verlag Tokyo
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The MAST-I Collaborative Group. (1995). Is Thrombolysis Useful for Acute Stroke Patients? The Experience of the MAST-I Study. In: Yamaguchi, T., Mori, E., Minematsu, K., del Zoppo, G.J. (eds) Thrombolytic Therapy in Acute Ischemic Stroke III. Springer, Tokyo. https://doi.org/10.1007/978-4-431-68459-6_23
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DOI: https://doi.org/10.1007/978-4-431-68459-6_23
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