Oncogenic Signaling of Tyrosine Kinase in Cancer: Challenges and Therapeutic Opportunities

ISSN: 1476-4598 (Online)

In this topical collection (34 articles)

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  1. Review

    Management of acquired resistance to EGFR TKI–targeted therapy in advanced non-small cell lung cancer

    Shang-Gin Wu, Jin-Yuan Shih Article:38
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  2. Review

    PTEN/PTENP1: ‘Regulating the regulator of RTK-dependent PI3K/Akt signalling’, new targets for cancer therapy

    Nahal Haddadi, Yiguang Lin, Glena Travis, Ann M. Simpson… Article:37
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  3. Review

    Advances in studies of tyrosine kinase inhibitors and their acquired resistance

    Qinlian Jiao, Lei Bi, Yidan Ren, Shuliang Song, Qin Wang, Yun-shan Wang Article:36
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  4. Review

    Pyruvate kinase M2 fuels multiple aspects of cancer cells: from cellular metabolism, transcriptional regulation to extracellular signaling

    Ming-Chuan Hsu, Wen-Chun Hung Article:35
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  5. Review

    Receptor tyrosine kinases (RTKs) in breast cancer: signaling, therapeutic implications and challenges

    Ramesh Butti, Sumit Das, Vinoth Prasanna Gunasekaran, Amit Singh Yadav… Article:34
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  6. Review

    KRAS oncogene in non-small cell lung cancer: clinical perspectives on the treatment of an old target

    Marta Román, Iosune Baraibar, Inés López, Ernest Nadal, Christian Rolfo… Article:33
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  7. Review

    Role of Non Receptor Tyrosine Kinases in Hematological Malignances and its Targeting by Natural Products

    Kodappully S. Siveen, Kirti S. Prabhu, Iman W. Achkar… Article:31
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  8. Review

    Role and targeting of anaplastic lymphoma kinase in cancer

    Carminia Maria Della Corte, Giuseppe Viscardi, Raimondo Di Liello… Article:30
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  9. Review

    Third generation EGFR TKIs: current data and future directions

    Chee-Seng Tan, Nesaretnam Barr Kumarakulasinghe, Yi-Qing Huang… Article:29
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  10. Review

    Oncogenic fusion proteins adopt the insulin-like growth factor signaling pathway

    Haim Werner, Shilhav Meisel-Sharon, Ilan Bruchim Article:28
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  11. Review

    The relevance of tyrosine kinase inhibitors for global metabolic pathways in cancer

    Michaela Poliaková, Daniel M. Aebersold, Yitzhak Zimmer… Article:27
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  12. Review

    Role of the HGF/c-MET tyrosine kinase inhibitors in metastasic melanoma

    Lucia Demkova, Lucia Kucerova Article:26
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  13. Review

    Tyrosine kinase inhibitors enhanced the efficacy of conventional chemotherapeutic agent in multidrug resistant cancer cells

    Shaocong Wu, Liwu Fu Article:25
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  14. Research

    The E3 ubiquitin ligase NEDD4 mediates cell migration signaling of EGFR in lung cancer cells

    Genbao Shao, Ranran Wang, Aiqin Sun, Jing Wei, Ke Peng, Qian Dai… Article:24
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