Overview
- Editors:
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John M. Walker
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Andrew J. Pollard
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BC Research Institute for Children’s and Women’s Health, Vancouver, Canada
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Martin C. J. Maiden
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Wellcome Trust Centre for the Epidemiology of Infectious Disease, Oxford, UK
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Table of contents (40 protocols)
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- Andrew J. Pollard, David Scheifele, Nancy Rosenstein
Pages 341-356
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- Keith A. Jolley, Rachel Urwin
Pages 357-373
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- F. Andrew I. Riordan, Andrew J. Pollard
Pages 375-410
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- Petter Brandtzaeg, Reidun Øvstebø, Peter Kierulf
Pages 427-439
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- Peter C. Giardina, Jerrold A. Weiss, Brad W. Gibson, Michael A. Apicella
Pages 441-458
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- Marcel van Deuren, Petter Brandtzaeg
Pages 459-486
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- Nina-Beate Liabakk, Anders Waage, Egil Lien, Jørgen Stenvik, Terje Espevik
Pages 487-497
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- Rudi G. J Westendorp, Tom W. J Huizinga
Pages 499-512
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- Jan A. Hazelzet, C.Erik Hack, Ronald de Groot
Pages 513-527
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- Anders G Sjöholm, Lennart Truedsson, Jens C. Jensenius
Pages 529-547
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- Simon Nadel, Iain Macintosh, Michael Levin
Pages 549-586
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- Paola Massari, Lee M. Wetzler
Pages 587-597
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- Mumtaz Virji, Laura Serino
Pages 599-619
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- Robert C. Read, Linda Goodwin
Pages 621-633
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- Colin Tinsley, Xavier Nassif
Pages 635-647
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- Robert S. Heyderman, Nigel J. Klein
Pages 649-661
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- Steven A. R. Webb, Paul R. Langford, J. Simon Kroll
Pages 663-677
About this book
Meningococcal septicemia and meningitis continue to be important causes of devastating illness, death, and long-term disability in both developed and resource-poor countries of the world. Few diseases have attracted as much public attention, or are as feared by parents and family members, as well as the medical staff who have to care for affected patients. The unexpected and unp- dictable occurrence of the disease in previously healthy children and young adults, its rapid progression, and the frequent occurrence of purpura fulminans with the resulting gangrene of limbs and digits and the requirement for mutilating s- gery, have all heightened both public and medical interest in the disease. Over the past two decades there has been a rapid increase in knowledge of many aspects of meningococcal disease as a result of intensive efforts by workers in many different fields: clinicians have studied the early presenting features and acute pathophysiology of the disorder; clinical scientists have explored the immunopathological mechanisms responsible for disease and have highlighted the important roles played by the host inflammatory response and pro-inflammatory cytokines in mediating damage to blood vessels and organs; microbiologists have developed new diagnostic methods; public health phy- cians and epidemiologists have improved surveillance techniques with the help of molecular tools provided by bacterial population biologists; and basic sci- tists have used the powerful new tools in molecular and cell biology to elucidate virulence mechanisms.
Reviews
"The editors invited the most skilled specialists in the world, 95 contributors, to share with the readers their knowledge of many aspects of meningococcal disease....The book is a brilliant and comprehensive review of the most recent methods for investigation of meningococcal disease and Neisseria meningitidis. It also includes detailed protocols, which should contribute to standardization of meningococcal investigation in the whole world and should allow different laboratories to obtain comparable results. The book is an excellent source of references. It is highly recommended to microbiologists, epidemiologists and clinicians dealing with meningococcal disease." - Folia Microbiologia
"The book claims to be "a comprehensive and authoritative review of meningococcal biology", "an interdisciplinary survey of recent advances and knowledge", to give "cutting-edge methods for the diagnosis, epidemiology and treatment of meningococcal disease", and it fully meets these standards. It has achieved its aim to join basic science with epidemiological and clinical aspects of the disease." - International Journal of Medical Microbiology
Editors and Affiliations
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BC Research Institute for Children’s and Women’s Health, Vancouver, Canada
Andrew J. Pollard
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Wellcome Trust Centre for the Epidemiology of Infectious Disease, Oxford, UK
Martin C. J. Maiden