Overview
- Top of their field scientists present the latest findings on RNA modification and editing
- First book with a special focus on the editing machinery involved and its effect on gene expression
Part of the book series: Topics in Current Genetics (TCG, volume 12)
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Table of contents (16 chapters)
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Front Matter
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Back Matter
Keywords
About this book
Naturally occurring RNA always contains numerous biochemically altered nucleotides. They are formed by enzymatic modification of the primary transcripts during the complex RNA maturation process designated RNA modification. A large number of enzymes catalyzing the formation of these modified nucleosides or converting one canonical base into another at the posttranscriptional level have been studied for many years, but only recently have systematic and comparative studies begun. The functions of individual enzymes and/or the modified/edited nucleosides in RNA, however, have remained largely ignored.
This book provides advance information on RNA modification, including the associated editing machinery, while offering the reader some perspective on the significance of such modifications in fine-tuning the structure and functions of mature RNA molecules and hence the ability to influence the efficiency and accuracy of genetic expression. Outstanding scientists who are actively working on RNA modification/editing processes have provided up-to-date information on these intriguing cellular processes that have been generated over the course of millions of years in all living organisms. Each review has been written and illustrated for a large audience of readers, not only specialists in the field, but also for advanced students or researchers who want to learn more about recent progress in RNA modification and editing.
Bibliographic Information
Book Title: Fine-Tuning of RNA Functions by Modification and Editing
Editors: Henri Grosjean
Series Title: Topics in Current Genetics
DOI: https://doi.org/10.1007/b95147
Publisher: Springer Berlin, Heidelberg
eBook Packages: Biomedical and Life Sciences, Biomedical and Life Sciences (R0)
Copyright Information: Springer-Verlag Berlin Heidelberg 2005
Hardcover ISBN: 978-3-540-24495-0Published: 03 May 2005
Softcover ISBN: 978-3-642-06381-7Published: 12 February 2010
eBook ISBN: 978-3-540-31454-7Published: 10 December 2004
Series ISSN: 1610-2096
Series E-ISSN: 1610-6970
Edition Number: 1
Number of Pages: XXIV, 442
Topics: Cell Biology, Biochemistry, general, Biological Techniques
Industry Sectors: Biotechnology, Pharma