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Ischemia-reperfusion in cardiac surgery

  • Book
  • © 1993

Overview

Part of the book series: Developments in Cardiovascular Medicine (DICM, volume 142)

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Table of contents (19 chapters)

  1. Pathophysiology of ischemia and reperfusion

  2. Concepts of cardioplegia

  3. Clinical application of cardioplegia

  4. Evaluation of cardioplegic methodology

Keywords

About this book

In open heart surgery, protection of the myocardium against injury by ischemia-reperfusion is an issue of utmost clinical interest. The knowledge on the causal mechanisms of myocardial injury in ischemia-reperfusion has greatly progressed in recent years, both to clinical and experimental research. This book provides a critical and comprehensive overview on the current discussion of myocardial protection in cardiac experimental research and surgery. Leading groups from Europe, the U.S. and Japan have contributed reviews of their special fields.
On the basic science side, major topics discussed are the mechanisms of stunning and lethal reperfusion injury, the role of the endothelium and leukocyte activation in postischemic myocardial dysfunction, and the differences between the adult and neonatal myocardium. On the clinical side, the major concepts and procedures for cardioplegic myocardial protection, their rationales, application and respective merits are discussed. In a third part of the book, possible approaches for the monitoring of myocardial injury during ischemia and reperfusion are evaluated, with particular attention to their intraoperative use.
This book brings together the scientific discussions on ischemia-reperfusion in experimental cardiology and cardiac surgery, a task needed for a long time. It is of general interest for clinicians as well as research workers and students in the cardiac field.

Editors and Affiliations

  • Institute of Physiology, Heinrich-Heine-University, Düsseldorf, Germany

    Hans Michael Piper

  • Department of Thoracic and Cardiovascular Surgery, Heinrich-Heine-University, Düsseldorf, Germany

    Claus J. Preusse

Bibliographic Information

  • Book Title: Ischemia-reperfusion in cardiac surgery

  • Editors: Hans Michael Piper, Claus J. Preusse

  • Series Title: Developments in Cardiovascular Medicine

  • DOI: https://doi.org/10.1007/978-94-011-1713-5

  • Publisher: Springer Dordrecht

  • eBook Packages: Springer Book Archive

  • Copyright Information: Kluwer Academic Publishers 1993

  • Hardcover ISBN: 978-0-7923-2241-2Published: 31 August 1993

  • Softcover ISBN: 978-94-010-4750-0Published: 23 October 2012

  • eBook ISBN: 978-94-011-1713-5Published: 06 December 2012

  • Series ISSN: 0166-9842

  • Edition Number: 1

  • Number of Pages: XIII, 458

  • Topics: Cardiac Surgery, Cardiology, Thoracic Surgery

  • Industry Sectors: Health & Hospitals

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