Synaptic Plasticity

Dynamics, Development and Disease

  • Michael R. Kreutz
  • Carlo Sala

Part of the Advances in Experimental Medicine and Biology book series (volume 970)

Table of contents

  1. Front Matter
    Pages i-ix
  2. Molecular Organization of the Pre- and Postsynaptic Scaffold

    1. Front Matter
      Pages 1-1
    2. Chiara Verpelli, Michael J. Schmeisser, Carlo Sala, Tobias M. Boeckers
      Pages 29-61
    3. Peter Penzes, Igor Rafalovich
      Pages 81-95
    4. Olena Bukalo, Alexander Dityatev
      Pages 97-128
  3. Molecular Dynamics of the Synapse

    1. Front Matter
      Pages 129-129
    2. Renato Frischknecht, Eckart D. Gundelfinger
      Pages 153-171
    3. Robert van den Berg, Casper C. Hoogenraad
      Pages 173-196
    4. Martin Heine
      Pages 197-219
    5. Bong-Kiun Kaang, Jun-Hyeok Choi
      Pages 221-240
    6. Madhav Sukumaran, Andrew C. Penn, Ingo H. Greger
      Pages 241-264
    7. Malgorzata Urbanska, Lukasz Swiech, Jacek Jaworski
      Pages 265-284
    8. Stefan Kindler, Hans-Jürgen Kreienkamp
      Pages 285-305
    9. Mirko Santello, Corrado Calì, Paola Bezzi
      Pages 307-331
  4. Synapse-to-Nucleus Communication

    1. Front Matter
      Pages 333-333
    2. Yasunori Hayashi, Ken-ichi Okamoto, Miquel Bosch, Kensuke Futai
      Pages 335-354
    3. Anna Karpova, Julia Bär, Michael R. Kreutz
      Pages 355-376

About this book


This book introduces the current concepts of molecular mechanisms in synaptic plasticity and provides a comprehensive overview of cutting-edge research technology used to investigate the molecular dynamics of the synapses. It explores current concepts on activity-dependent remodeling of the synaptic cytoskeleton and presents the latest ideas on the different forms of plasticity in synapses and dendrites. Synaptic Plasticity in Health and Disease not only supplies readers with extensive knowledge on the latest developments in research, but also with important information on clinical and applied aspects. Changes in spine synapses in different brain disease states, so-called synaptopathies, are explained and described by experts in the field. By outlining basic research findings as well as physiological and pathophysiological impacts on synaptic plasticity, the book represents an essential state-of-the-art work for scientists in the fields of biochemistry, molecular biology and the neurosciences, as well as for doctors in neurology and psychiatry alike.


dynamics of the synapse dynamics of the synapse plasticity in development plasticity in development synaptopathies synaptopathies the synapse the synapse transsynaptic signaling transsynaptic signaling

Editors and affiliations

  • Michael R. Kreutz
    • 1
  • Carlo Sala
    • 2
  1. 1., PG NeuroplasticityLeibniz Institute for NeurobiologyMagdeburgGermany
  2. 2., Institute of NeuroscienceCR6 CNR-IN Consiglio Nazionale delle RicMilanoItaly

Bibliographic information

  • DOI
  • Copyright Information Springer-Verlag/Wien 2012
  • Publisher Name Springer, Vienna
  • eBook Packages Biomedical and Life Sciences
  • Print ISBN 978-3-7091-0931-1
  • Online ISBN 978-3-7091-0932-8
  • Series Print ISSN 0065-2598
  • About this book
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