Skip to main content
  • Book
  • © 2012

Synaptic Plasticity

Dynamics, Development and Disease

  • Covers all aspects of molecular and cellular neurosciences regarding synaptic plasticity
  • With strong emphasis on synapthopathies
  • Includes cutting edge optical, genetic and proteomic tools and their application
  • Describes recent aspects of synaptic plasticity like retrograde transsynaptic signaling, trafficking, homeostatic plasticity and systems biology
  • Includes supplementary material: sn.pub/extras

Buy it now

Buying options

eBook USD 169.00
Price excludes VAT (USA)
  • Available as EPUB and PDF
  • Read on any device
  • Instant download
  • Own it forever
Softcover Book USD 219.99
Price excludes VAT (USA)
  • Compact, lightweight edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info
Hardcover Book USD 219.99
Price excludes VAT (USA)
  • Durable hardcover edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Other ways to access

This is a preview of subscription content, log in via an institution to check for access.

Table of contents (26 chapters)

  1. Synapse-to-Nucleus Communication

    1. Nuclear Calcium Signaling

      • C. Peter Bengtson, Hilmar Bading
      Pages 377-405
  2. Synaptic Dysfunction and Synaptopathies

    1. Front Matter

      Pages 431-431
    2. Synaptic Dysfunction and Intellectual Disability

      • Pamela Valnegri, Carlo Sala, Maria Passafaro
      Pages 433-449
    3. Synaptic Pathology of Down Syndrome

      • Craig C. Garner, Daniel Z. Wetmore
      Pages 451-468
    4. The Synaptic Pathology of Drug Addiction

      • Michel C. Van den Oever, Sabine Spijker, August B. Smit
      Pages 469-491
    5. Synaptic Dysfunction in Schizophrenia

      • Dong-Min Yin, Yong-Jun Chen, Anupama Sathyamurthy, Wen-Cheng Xiong, Lin Mei
      Pages 493-516
    6. Molecular and Cellular Aspects of Mental Retardation in the Fragile X Syndrome: From Gene Mutation/s to Spine Dysmorphogenesis

      • Silvia De Rubeis, Esperanza Fernández, Andrea Buzzi, Daniele Di Marino, Claudia Bagni
      Pages 517-551
    7. Synaptic Dysfunction in Parkinson’s Disease

      • Barbara Picconi, Giovanni Piccoli, Paolo Calabresi
      Pages 553-572
    8. Synaptic Dysfunction in Alzheimer’s Disease

      • Elena Marcello, Roberta Epis, Claudia Saraceno, Monica Di Luca
      Pages 573-601
    9. Erratum to: Gliotransmission and the Tripartite Synapse

      • Mirko Santello, Corrado Calì, Paola Bezzi
      Pages E1-E1
  3. Back Matter

    Pages 603-618

About this book

This book introduces the current concepts of molecular mechanisms in synaptic plasticity and provides a comprehensive overview of cutting-edge research technology used to investigate the molecular dynamics of the synapses. It explores current concepts on activity-dependent remodeling of the synaptic cytoskeleton and presents the latest ideas on the different forms of plasticity in synapses and dendrites. Synaptic Plasticity in Health and Disease not only supplies readers with extensive knowledge on the latest developments in research, but also with important information on clinical and applied aspects. Changes in spine synapses in different brain disease states, so-called synaptopathies, are explained and described by experts in the field. By outlining basic research findings as well as physiological and pathophysiological impacts on synaptic plasticity, the book represents an essential state-of-the-art work for scientists in the fields of biochemistry, molecular biology and the neurosciences, as well as for doctors in neurology and psychiatry alike.

Reviews

From the reviews:

“Vital to the library of any neurologist or organic psychologist for its long-term reference value.” (The Electric Review, October, 2012)

Editors and Affiliations

  • , PG Neuroplasticity, Leibniz Institute for Neurobiology, Magdeburg, Germany

    Michael R. Kreutz

  • , Institute of Neuroscience, CR6 CNR-IN Consiglio Nazionale delle Ric, Milano, Italy

    Carlo Sala

About the editors

Michael R. Kreutz studied psychology, philosophy and linguistics at the University of Münster, Germany. He completed his PhD in Behavioral Neurosciences at the Ruhr University in Bochum, Germany and subsequently received a stipend from the Centers for Brain Research and Metabolism to become a research fellow at the Department of Brain and Cognitive Sciences at MIT, USA. From 1990 to 1993 he was staff scientist in the Department of Molecular Neuroendocrinology at the Max Planck Institute for Experimental Medicine in Göttingen, Germany. In 1993, he received a research leader position at the University of Madgeburg. From 1998 to 2007 he was head of the independent research group “Molecular Mechanism of Plasticity” at the Leibniz Institute for Neurobiology in Magdeburg. Since 2007 he has been tenured senior research group leader and head of the Neuroplasticity research group at the Leibniz Institute in Magdeburg.

Carlo Sala studied Medicine at the University of Milano, Italy. He completed his PhD in Pharmacology and Toxicology at the University of Milano in 1997. From 1998 to 2001 he was a postdoctoral research fellow at the Howard Hughes Medical Institute, Department of Neurobiology, Harvard Medical School in Boston, USA. In these years he received fellowships from the Giovanni Armenise-Harvard Foundation, the Consiglio Nazionnale delle Richerche (CNR) and the Howard Hughes Medical Institute. From 2001 to 2005 he held a research assistant position at CNR Neuroscience Institute in Milano, Italy and since 2006 he has been an assistant researcher at the CNR Neuroscience Institute in Milano.

Bibliographic Information

  • Book Title: Synaptic Plasticity

  • Book Subtitle: Dynamics, Development and Disease

  • Editors: Michael R. Kreutz, Carlo Sala

  • DOI: https://doi.org/10.1007/978-3-7091-0932-8

  • Publisher: Springer Vienna

  • eBook Packages: Biomedical and Life Sciences, Biomedical and Life Sciences (R0)

  • Copyright Information: The Editor(s) (if applicable) and The Author(s), under exclusive license to Springer-Verlag GmbH, AT, part of Springer Nature 2012

  • Hardcover ISBN: 978-3-7091-0931-1Published: 18 February 2012

  • Softcover ISBN: 978-3-7091-1732-3Published: 17 April 2014

  • eBook ISBN: 978-3-7091-0932-8Published: 17 February 2012

  • Edition Number: 1

  • Number of Pages: X, 622

  • Topics: Neurosciences, Neurology, Neurobiology

  • Industry Sectors: Biotechnology, Consumer Packaged Goods, Health & Hospitals, Pharma

Buy it now

Buying options

eBook USD 169.00
Price excludes VAT (USA)
  • Available as EPUB and PDF
  • Read on any device
  • Instant download
  • Own it forever
Softcover Book USD 219.99
Price excludes VAT (USA)
  • Compact, lightweight edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info
Hardcover Book USD 219.99
Price excludes VAT (USA)
  • Durable hardcover edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Other ways to access