Oncogene-Induced Senescence

Methods and Protocols

  • Mikhail A.┬áNikiforov
Part of the Methods in Molecular Biology book series (MIMB, volume 1534)

Table of contents

  1. Front Matter
    Pages i-xi
  2. Anna Bianchi-Smiraglia, Brittany C. Lipchick, Mikhail A. Nikiforov
    Pages 1-15
  3. Lena Lau, Gregory David
    Pages 17-30
  4. Michael Shtutman, Bey-Dih Chang, Gary P. Schools, Eugenia V. Broude
    Pages 31-39
  5. Dorothy N. Y. Fan, Clemens A. Schmitt
    Pages 41-52
  6. Amaresh C. Panda, Kotb Abdelmohsen, Myriam Gorospe
    Pages 79-87
  7. Hengrui Zhu, Linh Le, Hsin-Yao Tang, David W. Speicher, Rugang Zhang
    Pages 127-137
  8. Rabii Ameziane-El-Hassani, Corinne Dupuy
    Pages 139-145
  9. Mikhail A. Nikiforov, Donna S. Shewach
    Pages 165-173
  10. Andrew Joselow, Darren Lynn, Tamara Terzian, Neil F. Box
    Pages 175-184
  11. Kwan-Hyuck Baek, Sandra Ryeom
    Pages 185-198
  12. Mekayla Storer, William M. Keyes
    Pages 199-210

About this book

Introduction

This book offers in a single volume a unique collection of the state-of-the-art experimental procedures utilized for the induction, detection, and modeling of this complex cellular program of oncogene-induced senescence. The book encompasses protocols for studying this multi-step program in human specimens and a variety of experimental models including cultured mammalian cells, laboratory mice, and Drosophila melanogaster, as well as offering a description of high throughput approaches. Written for the highly successful Methods in Molecular Biology series, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. 

Authoritative and practical, Oncogene-Induced Senescence: Methods and Protocols represents a valuable asset for a wide audience of medical oncologists and researchers in the fields of oncology, molecular and cellular biology, biochemistry, and animal development.

Keywords

Senescent cells Phenotypes Cellular processes Oncology Oncoproteins

Editors and affiliations

  • Mikhail A.┬áNikiforov
    • 1
  1. 1.Department of Cell Stress BiologyRoswell Park Cancer InstituteBuffaloUSA

Bibliographic information

  • DOI https://doi.org/10.1007/978-1-4939-6670-7
  • Copyright Information Springer Science+Business Media New York 2017
  • Publisher Name Humana Press, New York, NY
  • eBook Packages Springer Protocols
  • Print ISBN 978-1-4939-6668-4
  • Online ISBN 978-1-4939-6670-7
  • Series Print ISSN 1064-3745
  • Series Online ISSN 1940-6029
  • About this book

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