Overview
- Includes cutting-edge methods and protocols
- Provides step-by-step detail essential for reproducible results
- Contains key notes and implementation advice from the experts
Part of the book series: Methods in Molecular Biology (MIMB, volume 1793)
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Table of contents (16 protocols)
Keywords
About this book
This volume details fast-moving research while providing in-depth descriptions of methods and analytical approaches that are helping to understand the genome and how it is related to complex diseases. Chapters guide the reader through common and rare variation, gene-gene and gene-environment interactions and state-of-the-art approaches for the synthesis of genome-wide and gene expression data. Novel approaches for associations in the HLA region, family-based designs, Mendelian Randomization and Copy Number Variation are also presented. The volume concludes with the challenges researchers face while moving from identifying variants to their functional role and potential drug targets. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, a thorough presentation of methods and approaches and tips on troubleshooting and avoiding known pitfalls.
Editors and Affiliations
Bibliographic Information
Book Title: Genetic Epidemiology
Book Subtitle: Methods and Protocols
Editors: Evangelos Evangelou
Series Title: Methods in Molecular Biology
DOI: https://doi.org/10.1007/978-1-4939-7868-7
Publisher: Humana New York, NY
eBook Packages: Springer Protocols
Copyright Information: Springer Science+Business Media, LLC, part of Springer Nature 2018
Hardcover ISBN: 978-1-4939-7867-0Published: 07 June 2018
Softcover ISBN: 978-1-4939-9309-3Published: 25 July 2019
eBook ISBN: 978-1-4939-7868-7Published: 06 June 2018
Series ISSN: 1064-3745
Series E-ISSN: 1940-6029
Edition Number: 1
Number of Pages: X, 299
Number of Illustrations: 12 b/w illustrations, 23 illustrations in colour
Topics: Human Genetics