Overview
- Ex vivo and in vitro model systems
- In-depth discussion of four increasing tumor types
- Five key signaling pathways that can be targeted
- Includes new and emerging concepts and technologies
Part of the book series: Cancer Metastasis - Biology and Treatment (CMBT, volume 8)
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Table of contents (13 chapters)
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Front Matter
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Back Matter
Keywords
About this book
Cancer Morbidity and mortality result from invasive and metastatic spread. Currently, no therapies are aimed at the underlying mechanisms that enable this progression due to only nascent recognition of the distinct biology which occurs only during tumor dissemination. Recent advances have highlighted the central role of cell motility during the dynamic and transient process of tumor invasion and metastasis. This book includes state-of-the-art updates by international leaders in these studies. Chapters first present the novel model systems that enable new investigations and insights. Chapters then describe in depth the key processes and molecules that may be therapeutically targeted. Finally, the role of cell motility and its signals is explored in a number of key tumor types. This compilation should be useful to researchers in basic and translational oncology as well as those developing novel agents to prevent tumor invasion and metastasis.
Editors and Affiliations
Bibliographic Information
Book Title: Cell Motility in Cancer Invasion and Metastasis
Editors: Alan Wells
Series Title: Cancer Metastasis - Biology and Treatment
DOI: https://doi.org/10.1007/b103440
Publisher: Springer Dordrecht
eBook Packages: Biomedical and Life Sciences, Biomedical and Life Sciences (R0)
Copyright Information: Springer Science+Business Media B.V. 2006
Hardcover ISBN: 978-1-4020-4008-5Published: 02 February 2006
Softcover ISBN: 978-90-481-7011-1Published: 20 November 2010
eBook ISBN: 978-1-4020-4009-2Published: 22 June 2006
Series ISSN: 1568-2102
Series E-ISSN: 2215-1648
Edition Number: 1
Number of Pages: XIII, 353
Topics: Cancer Research, Oncology, Biomedicine general, Life Sciences, general
Industry Sectors: Biotechnology, Consumer Packaged Goods, Health & Hospitals, Pharma