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Red Cell Shape

Physiology, Pathology, Ultrastructure

  • Conference proceedings
  • © 1973

Overview

Editors:
  1. Marcel Bessis

    1. Institut de Pathologie Cellulaire, Hôpital de Bicêtre, Le Kremlin-Bicêtre, France

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  2. Robert I. Weed

    1. Depts. of Medicine and of Radiation Biology and Biophysics, University of Rochester School of Medicine and Dentistry, Rochester, USA

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  3. Pierre F. Leblond

    1. Institut de Pathologie Cellulaire, Hôpital de Bicêtre, Le Kremlin-Bicêtre, France

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Table of contents (18 papers)

  1. Front Matter

    Pages i-viii
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  2. Red Cell Shapes and Nomenclature

    1. Red Cell Shapes. An Illustrated Classification and its Rationale

      • M. Bessis
      Pages 1-25

    2. Nomenclature of Red Cell Shapes A commentary

      • G. Brecher
      Pages 27-30

    3. Spiculed Erythrocytes after Splenectomy Acanthocytes or Non-Specific Poikilocytes ?

      • G. Brecher, J. E. Haley, R. O. Wallerstein
      Pages 31-34

  3. Discocyte-Echinocyty and Discocyte-Stomatocyte Transformations

    1. Erythrocyte Shape Alteration « In Vitro » : Relationship to Plasma and Cellular Factors Abstract

      • M. A. Lichtman, G. V. Marinetti
      Pages 35-36

    2. The Role of Lysolecithin Formed in Plasma on the Discocyte-Echinocyte Transformation A commentary

      • C. Feo
      Pages 37-40

    3. Red Cell Membrane Shape and Stability : Relation to Cell Lipid Renewal Pathways and Cell ATP

      • S. B. Shohet, J. E. Haley
      Pages 41-50

    4. Quantitative Study of Factors which Control Shape Transformations of Human Red Blood Cells of Constant Volume

      • J. F. Hoffman
      Pages 51-54

    5. Calcium-pH Interactions in the Production of Shape Change in Erythrocytes

      • R. I. Weed, B. Chailley
      Pages 55-68

    6. Membrane Fragmentation and Ca++-Membrane Interaction : Potential Mechanisms of Shape Change in the Senescent Red Cell

      • P. L. La Celle, F. H. Kirkpatrick, M. P. Udkow, B. Arkin
      Pages 69-78

    7. Divalent Cation Content of Normal and ATP-Depleted Erythrocytes and Erythrocyte Membranes

      • M. A. Lichtman, R. I. Weed
      Pages 79-93
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Keywords

About this book

This monograph is a collection of invited contributions from a group of investiga­ tors who share a common interest in the interrelationships between the shape, struc­ ture, and functional characteristics of normal and pathologic erythrocytes. Most of the authors participated in a workshop on red cell shape held in June, 1972 at the Institute of Cell Pathology, Hopital de Bicetre, Paris. We hope that these various contributions on the physiology, pathology, and ultrastructure of red cell shape will be useful and stimulating for other investigators interested in the correlation of shape and structure with the biochemistry and biophysics of the red cell. The text is divided into four sections. Section I deals with red cell shape, including the presentation of a rational descriptive nomenclature and a discussion of post­ splenectomy changes. Section II deals with biochemical factors that underlie the disco­ cyte-echinocyte (crenated) and discocyte-stomatocyte (cup-shaped) transformation. This section includes discussions of plasma factors, and of the biochemical dynamics of erythrocyte lipids and consideration of the effects of such factors as cellular ATP, calcium, aging, and various chemical agents as determinants of shape. Section III, which deals with biophysical measurements, includes studies of the deformability of cells of different shapes, descriptions of ways to define precisely the geometric dimensions of the red cell under various circumstances, and a model of membrane structure, which is proposed to account for the dimensions of red cells that undergo shape change.

Editors and Affiliations

  • Institut de Pathologie Cellulaire, Hôpital de Bicêtre, Le Kremlin-Bicêtre, France

    Marcel Bessis, Pierre F. Leblond

  • Depts. of Medicine and of Radiation Biology and Biophysics, University of Rochester School of Medicine and Dentistry, Rochester, USA

    Robert I. Weed

Bibliographic Information

  • Book Title: Red Cell Shape

  • Book Subtitle: Physiology, Pathology, Ultrastructure

  • Editors: Marcel Bessis, Robert I. Weed, Pierre F. Leblond

  • DOI: https://doi.org/10.1007/978-3-642-88062-9

  • Publisher: Springer Berlin, Heidelberg

  • eBook Packages: Springer Book Archive

  • Copyright Information: Masson & Cie, Editeurs, Paris 1973

  • Softcover ISBN: 978-3-642-88064-3Published: 22 April 2012

  • eBook ISBN: 978-3-642-88062-9Published: 06 December 2012

  • Edition Number: 1

  • Number of Pages: VIII, 180

  • Topics: Hematology

  • Industry Sectors: Biotechnology, Health & Hospitals, Pharma

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