Red Cell Shape pp 105-113 | Cite as

Hemolysis, Induced by Pulsed Laser Irradiation, Transmitted along Rouleaux of Human Red Blood Cells

  • P. B. Canham
Conference paper


The human red blood cell has the equilibrium shape of an 8 μm biconcave disc in isotonic buffered Ringer solution. If the cell membrane is damaged the cell swells to a 6 μm sphere and hemolyzes. In this study we caused individual red cells to lyse by focusing on them through a microscope a single pulse from a ruby laser. The target cell would lyse more rapidly if more energy was used in the laser pulse. Of particular interest was the observation that if a target cell was situated in a rouleau of cells then cells adjacent to the target cell would lyse as well.


Target Cell Pulse Laser Irradiation Ruby Laser Hemoglobin Solution Physical Shear 
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Copyright information

© Masson & Cie, Editeurs, Paris 1973

Authors and Affiliations

  • P. B. Canham

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