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Degradation Phenomena on Polymeric Biomaterials

  • Conference proceedings
  • © 1992

Overview

Editors:
  1. Heinrich Planck

    1. Institut für Textil- und Verfahrenstechnik, Denkendorf, Germany

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  2. Martin Dauner

    1. Institut für Textil- und Verfahrenstechnik, Denkendorf, Germany

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  3. Monika Renardy

    1. Institut für Textil- und Verfahrenstechnik, Denkendorf, Germany

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Table of contents (14 papers)

  1. Front Matter

    Pages I-X
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  2. Evaluation of Degradation in Vitro: Physical, Chemical and Biological Test Methods

    1. Testing of Pur-Biomaterials for Enzymaticauy Induced Degradation: An in Vitro Study

      • B. Glasmacher-Seiler, J. Jonas, G. Schädlich, H. Reul, G. Rau
      Pages 1-8

    2. Chemical Alteration of Biomer™ as a Result of Oxidative Degradation

      • Bonnie J. Tyler, Buddy D. Ratner
      Pages 9-23

    3. In-Vitro Degradation Test for Screening of Biomaterials

      • C. Welling, H. Schwengler, B. Strahl
      Pages 25-36

  3. Degradation Phenomena of “Non-Degradable” Biomaterials

    1. The Biodegradation of Nondegradable Polymers

      • K. B. Stokes, P. W. Urbanski
      Pages 37-58

    2. A Comparison of In Vivo Degradation of Novel Polyurethanes with Performance in In Vitro Accelerated Tests

      • A. Brandwood, K. R. Noble, K. Schindhelm, G. F. Meijs, P. A. Gunatillake, R. C. Chatelier et al.
      Pages 59-66

  4. The Resorbable Biomaterials and their Degradation Mechanisms

    1. Accelerated Degradation Test on Resorbable Polymers

      • Berthold Buchholz
      Pages 67-76

    2. Kinetics of Resorption of Different Suture Materials Depending on the Implantation Site and the Species

      • M. A. Scherer, H.-J. Früh, R. Ascherl, H. Mau, W. Siebels, G. Blümel
      Pages 77-96

  5. The Influence of Polymer Modification and Processing Parameters on Degradation

    1. Tissue Response to Resorbable Synthetic Polymers

      • D. F. Gibbons
      Pages 97-105

    2. In Vitro Degradation of Polylactides Depending on Different Processes

      • M. Dauner, E. Müller, B. Wagner, H. Planck
      Pages 107-122

    3. Tissue Response to Pre-Degraded Poly(L-Lactide)

      • F. R. Rozema, R. R. M. Bos, G. Boering, A. J. Nijenhuis, A. J. Pennings, H. W. B. Jansen et al.
      Pages 123-131

  6. Clinical Application of Resorbable Biomaterials: Suture

    1. Modern Absorbable Suture Materials and Biodegradable Anastomotic Rings in Gastrointestinal Surgery

      • A. Thiede, B. Lünstedt
      Pages 133-151

    2. A Novel Bioabsorbable Monofilament Surgical Suture Made From (ε -Caprolactone, L-Lactide) Copolymer

      • Tatsuo Nakamura, Yasuhiko Shimizu, Teruo Matsui, Norihito Okumura, Suong Hyu Hyon, Kouji Nishiya
      Pages 153-162

  7. Clinical Application of Resorbable Biomaterials in Reconstructive Surgery

    1. Clinical Application of Resorbable Biomaterials in Reconstructive Surgery

      • K. E. Rehm
      Pages 163-176

    2. Biodegradable PLA Versus Stainless Steel Intramedullary Devices for Fracture Fixation. A Comperative Histological Study

      • M. van der Elst, A. R. A. Dijkema, C. P. A. T. Klein, P. Patka, H. J. Th. M. Haarman
      Pages 177-183

  8. Back Matter

    Pages 185-197
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Keywords

About this book

Tradi tionally, the International lTV - Conferences on Biomate­ rials are focussing on problems in Biomedical Engineering, problems, which are still unsolved, of main interest, and which are of interdisciplinary character. In 1983, the Division of Biomedical Engineering of the Institute of Textile Technology and Chemical Engineering, Denkendorf, started wi th a conference about the use of polyurethanes in biomedicine. Three years later,. in 1986, progress in development and use of polyurethanes was selected as conference topic. It had to be realized that degradation problems were still dominating the discussions. The main discussion topics were: What are the causes for the degradation? How can one prevent them? What are the degradation products, and do they affect the human body? How can one simu­ late the degradation? How can one accelerate the in vitro tests and how can the results predict the in vivo behaviour of the material? How do in vitro tests correlate with animal tests and the behaviour in the human body? At the third conference in 1989, the speakers focused on the use of textiles in medicine. Again the problem of degradation was discussed intensively and demonstrated by the failure of textile implants, the degradation of aramide polymers or the degradation of resorbable suture materials. The examples make clear, that degradation may be a desired or undesired property of an implant.

Editors and Affiliations

  • Institut für Textil- und Verfahrenstechnik, Denkendorf, Germany

    Heinrich Planck, Martin Dauner, Monika Renardy

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