Tissue Response to Pre-Degraded Poly(L-Lactide)
Poly(L-lactide) is a member of a group biodegradable aliphatic poly(lactone)esters which have found important use as biomaterials e. g. in prosthetics, sutures, and drug delivery systems. As-polymerized, high molecular weight poly(L-laetide) (PLLA) as synthesized according to Leenslag et al.1has been successfully used for fracture fixation and orbital floor reconstruction in animals and humans2-5. PLLA is considered to be a fully resorbable, biocompatible material6.
KeywordsHydrolysis Lactate Steam Citrate Biodegradation
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