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In Vitro Effects of Mineral Dusts

Third International Workshop

  • Book
  • © 1985

Overview

Editors:
  1. Ernst G. Beck

    1. Hygiene-Institut, Universität Gießen, Gießen, Germany

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    You can also search for this editor in PubMed   Google Scholar

  2. Jean Bignon

    1. Unité INSERM, CHU Henri Mondor, Creteil Cedex, France

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    You can also search for this editor in PubMed   Google Scholar

Part of the book series: Nato ASI Subseries G: (ASIG, volume 3)

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Table of contents (72 chapters)

  1. Front Matter

    Pages I-XIII
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  3. Minerals and Target Cells

    1. Front Matter

      Pages 7-7
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    2. Role of Physicochemical Properties of Minerals

      1. Physicochemical Properties of Minerals Relevant to Biological Activities: State of the Art
        • A. M. Langer, R. P. Nolan
        Pages 9-24
      2. Surface Active Sites and Catalytic Properties of Asbestos Mineral. Possible Consequence for their Activity in Biological Medium
        • L. Bonneau, R. Zalma, J. Guignard, H. Pezerat, D. Mansuy, M. Fonecave
        Pages 25-30
      3. Investigations into the Mechanisms of Asbestos Toxicity
        • G. L. Fisher, K. L. McNeill, B. T. Mossman, J. Marsh, A. R. McFarland, R. W. Hart
        Pages 31-38
      4. Particle Size and Chemically-Induced Variability in the Membrolytic Activity of Quartz: Preliminary Observations
        • R. P. Nolan, A. M. Langer, K. W. Foster
        Pages 39-50

    3. Cellular Effects of Mineral Dusts

      1. The Target Cells for Inhaled Mineral Dusts
        • A. R. Brody, L. Hill
        Pages 53-58
      2. A Potential Role for Oxygen Radicals in Mineral Dust-Induced Lung Injury: Lessons from Lung Injury from Hyperoxia
        • J. E. Repine
        Pages 59-65
      3. Mechanisms of Toxic Injury by Asbestos Fibers: Role of Oxygen-Free Radicals
        • B. T. Mossman, J. P. Marsh
        Pages 66-74
      4. Release of Superoxide Anion and Hydrogen Peroxide by Macrophages in Response to Asbestos
        • K. Donaldson, J. Slight, R. E. Bolton
        Pages 75-81
      5. Stimulation of Neutrophil Chemiluminescence by Alveolar Macrophages from Patients Exposed to Asbestos
        • M. Bérardi, R. Bégin, M. Rola-Pleszczynski
        Pages 83-91
      6. Broncho Alveolar Lavage in Coal Worker’s Pneumoconiosis: Oxidant and Antioxidant Activities of Alveolar Macrophages
        • C. Voisin, B. Wallaert, C. Aerts, J. M. Grosbois
        Pages 93-100
      7. Summary and Synthesis of Part I. Role of Physico-Chemical Properties of Minerals (A)
        • J. Dunnigan, K. Robock
        Pages 101-102
      8. Summary and Synthesis of Part I. Cellular Effects of Mineral Dusts (B)
        • J. Dunnigan, A. Scharmann
        Pages 103-105

  4. Immune Responses and Immunotoxicity

    1. Front Matter

      Pages 107-107
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    2. Immune Responses Induced by Mineral Dusts

      • R. P. Daniele
      Pages 109-119

    3. Effect of Asbestos Preparations on the Random Migration Pattern of Rabbit Alveolar Macrophages

      • Q. N. Myrvik
      Pages 121-127

    4. Inhaled Asbestos Fibers Produce Complement-Derived Chemotactic Factor(s) on Alveolar Surfaces

      • D. B. Warheit, G. George, L. H. Hill, R. Snyderman, A. R. Brody
      Pages 129-138

    5. Immunoregulation During Experimental Asbestosis

      • J. Stankova, S. Gouin, R. Bégin, M. Rola-Pleszczynski
      Pages 139-147
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Keywords

About this book

The Third International \~orkshop on "The in Vitro Effects of Mineral Dusts" was held on October 1 - 4, 1984 in Schluchsee, Black Forest, Federal Republic of Germany. In six sessions, 93 participants from 14 countries (USA 32, France 17, United Kingdom 12, FRG 11, Canada 9, Belgium 3, Hungary 1, Italy 2, India 1, Nether­ lands 1, Norway 1, Poland 1, Portugal 1, Turkey 1) treated and discussed the following subjects: - Significance of the physico-chemical properties of inhalable mineral dusts (mine dusts, asbestos, Man-Made Mineral Fibres - MMMF). - Cellular effects of inhalable mineral dusts with special regard to target ce 11 s. - Immune response and immune toxicity. - Carcinogenicity and interrelated genotoxic and non-genotoxic effects. - Effect of cell metabolism in combination with inflammation and fibrogenesis. - Significance and credibility of in vitro test systems. For the pathogenesis of biological effects and diseases caused by inhalable mineral dusts a number of factors may be significant such as: - Type of dust - Dose of dust - Size and shape of dust particles, and especially - Surface properties of dust particles, which inter alia determine the - sorption properties, e.g. for environmental substances.

Editors and Affiliations

  • Hygiene-Institut, Universität Gießen, Gießen, Germany

    Ernst G. Beck

  • Unité INSERM, CHU Henri Mondor, Creteil Cedex, France

    Jean Bignon

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