A Potential Role for Oxygen Radicals in Mineral Dust-Induced Lung Injury: Lessons from Lung Injury from Hyperoxia
Part of the
NATO ASI Series
book series (volume 3)
There is considerable interest currently in determining the contribution of toxic oxygen metabolites (commonly called “oxygen radicals”) to the development of lung injury. As requested, the purpose of this article will be twofold. First, we will briefly present a summary of our research about the potential contributions of O2 radicals to the development of lung injury from hyperoxia. Second, we will propose a number of possibilities for the involvement of O2 radicals in the pathogenesis of lung injuries from inhaled mineral dusts. The latter is wholly speculative and should be considered in the context of the other research presented in this book and elsewhere.
KeywordsLung Injury Alveolar Macrophage Adult Respiratory Distress Syndrome Phorbol Myristate Acetate Mineral Dust
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.
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© Springer-Verlag Berlin Heidelberg 1985