Immune Responses Induced by Mineral Dusts
Inhalation of dusts of silica and beryllium metal can produce granulomatous interstitial lung disease. Both agents are also recognized to have important effects on the host’s local and systemic immune system. For beryllium, there appears to be a primary role in the pathogenesis of disease and the development of immune abnormalities; for silica, a wide variety of secondary immune phenomena may result (Vigliani and Pernis 1963).
KeywordsAlveolar Macrophage Latex Particle Lung Fibroblast Mineral Dust Sublethal Dose
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