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Receptors and Other Targets for Toxic Substances

Proceedings of the European Society of Toxicology, Meeting Held in Budapest, June 11–14, 1984

  • Conference proceedings
  • © 1985

Overview

Editors:
  1. Philip L. Chambers

    1. Department of Pharmacology and Therapeutics, Trinity College, University of Dublin, Dublin 2, Ireland

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  2. Eszter Cholnoky

    1. Pharmacological Research Centre, Toxicological Service, Chemical Works of Gedeon Richter Ltd., Budapest, Hungary

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    You can also search for this editor in PubMed   Google Scholar

  3. Claire M. Chambers

    1. Department of Pharmacology and Therapeutics, Trinity College, University of Dublin, Dublin 2, Ireland

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    You can also search for this editor in PubMed   Google Scholar

Part of the book series: Archives of Toxicology (TOXICOLOGY, volume 8)

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Table of contents (121 papers)

  1. Toxic Effects on the Gastrointestinal Tract

    1. The Incidence of Neoplasms in Syrian Hamsters with Particular Emphasis on Intestinal Neoplasia

      • A. Fabry
      Pages 124-127

  2. Toxic Effects on Haemostasis and Blood

    1. Front Matter

      Pages 129-129
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    2. Thrombogenic Effects of Xenobiotics

      • G. Zbinden, L. Grimm
      Pages 131-141

    3. Toxicologically Relevant Disturbances of Haemostasis

      • H.-P. Klöcking
      Pages 142-147

    4. Effects of Organic Solvents on Erythrocyte Membrane Acetylcholine Esterase Activity

      • M. Korpela, H. Tähti
      Pages 148-151

    5. Changes of Haemostaseological Variables in Carbon Tetrachloride Poisoning in Rats

      • H.-P. Klöcking, H. Müller, F. Markwardt
      Pages 152-155

    6. Influence of Antithrombin III on Carbon Tetrachloride Intoxication of Rabbits

      • H. Ronneberger
      Pages 156-159

    7. Increased Serum Alkaline Phosphatase Activity in Beagle Dogs: Mechanism, Diagnostic Considerations

      • S. Elek, I. Léránt, I. Polgári, G. Cseh
      Pages 160-160

    8. Interaction of Rodenticides and Humic Acids — Effects on Prothrombin Activity

      • S. Golbs, V. Fuchs
      Pages 161-161

  3. Interpretation of Concentrations of Toxic Agents During Drug Safety Studies

    1. Front Matter

      Pages 163-163
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    2. Reasons for Monitoring Kinetics in Safety Evaluation Studies

      • D. R. Hawkins, L. F. Chasseaud
      Pages 165-172

    3. A Decision Tree Approach for the Application of Drug Metabolism and Kinetic Studies to in Vivo and in Vitro Toxicological and Pharmacological Testing

      • P. H. Bach, J. W. Bridges
      Pages 173-188

    4. Theoretical Aspects Pertinent to the Interpretation of Concentration Data

      • W. Riess
      Pages 189-195

    5. How to Identify Compounds Posing Problems in Absorption, Distribution and Elimination

      • K. Schmid
      Pages 196-204

    6. A Questionnaire Assessing the Involvement of Toxicologists in Metabolism and Kinetics

      • W. Riess
      Pages 205-207

    7. A Stochastic Approach in the Evaluation of Plasma Curves with Enterohepatic Recycling

      • M. Tarr, A. Eöry
      Pages 208-210

    8. Endotoxin and Pharmacokinetics of Rifampicin

      • J. Lavický, L. Čeleda, Z. Urbanová, J. Květina, J. Vaněček, H. Rašková
      Pages 211-215

    9. Local Toxicity and Pharmacokinetics After Intramuscular or Intralipomatous Injection of Different Drugs in Pigs

      • O. Svendsen, L. Blom, T. Aaes-Jørgensen, J.-J. Larsen
      Pages 216-217

    10. Distribution of Metabolites of the Potent β-Adrenoceptor Blocking Drug B 24/76 in Different Tissues of Rats Under Toxic Conditions

      • I. Amon, A. Baumann, B. Hartmann, K.-P. Henschel, A. Müller
      Pages 218-218

  4. Functional and Morphological Changes in the Inner Ear

    1. Front Matter

      Pages 219-219
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Keywords

Editors and Affiliations

  • Department of Pharmacology and Therapeutics, Trinity College, University of Dublin, Dublin 2, Ireland

    Philip L. Chambers, Claire M. Chambers

  • Pharmacological Research Centre, Toxicological Service, Chemical Works of Gedeon Richter Ltd., Budapest, Hungary

    Eszter Cholnoky

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