Changes of Haemostaseological Variables in Carbon Tetrachloride Poisoning in Rats

  • H.-P. Klöcking
  • H. Müller
  • F. Markwardt
Conference paper
Part of the Archives of Toxicology book series (TOXICOLOGY, volume 8)

Abstract

On application of carbon tetrachloride to rats disturbances of haemostasis were observed. Antithrombin III and 4-amidinophenylpyruvic acid were found to exert a beneficial action on these disturbances. However, the thrombin inhibitors had no influence on hepatotoxicity and lethality.

Key words

Carbon tetrachloride Disturbances of haemostasis Antithrombin III 4-Amidinophenylpyruvic acid Rats 

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References

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Copyright information

© Springer-Verlag 1985

Authors and Affiliations

  • H.-P. Klöcking
    • 1
  • H. Müller
    • 1
  • F. Markwardt
    • 1
  1. 1.Institute of Pharmacology and ToxicologyMedical Academy ErfurtErfurtGDR

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