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Estrogens and Antiestrogens II

Pharmacology and Clinical Application of Estrogens and Antiestrogen

  • Michel Oettel
  • Ekkehard Schillinger

Part of the Handbook of Experimental Pharmacology book series (HEP, volume 135 / 2)

Table of contents

  1. Front Matter
    Pages I-XXXIII
  2. Part 5: Pharmacology of Estrogens and Antiestrogens

    1. Front Matter
      Pages 1-1
    2. K.-H. Fritzemeier, C. Hegele-Hartung
      Pages 3-94
    3. G. Kuiper, M. Warner, J.-Å Gustafsson
      Pages 95-104
    4. G. Söderqvist, B. Von Schoultz
      Pages 113-128
    5. G. Samsioe
      Pages 129-140
    6. B. Winding, H. JØrgensen, C. Christiansen
      Pages 141-149
    7. R. Gallo, M. Stomati, A. Spinetti, F. Petraglia, A. R. Genazzani
      Pages 151-162
    8. L. Sahlin, B. von Schoultz
      Pages 163-178
    9. A. E. Wakeling
      Pages 179-194
    10. E. V. Jensen
      Pages 195-203
    11. S. R. D. Johnston, E. Anderson, M. Dowsett, A. Howell
      Pages 205-221
    12. A. S. Bhatnagar, W. R. Miller
      Pages 223-230
  3. Part 6: Kinetics and Toxicology of Estrogens and Antiestrogens

    1. Front Matter
      Pages 259-259
    2. H. Zimmermann
      Pages 323-351
  4. Part 7: Clinical Application and Potential of Estrogens and Antiestrogens

    1. Front Matter
      Pages 361-361
    2. H. Kuhl
      Pages 363-407
    3. H. L. Jørgensen, B. Winding
      Pages 409-422
    4. G. Samsioe
      Pages 423-430
    5. Michel Oettel, Ekkehard Schillinger
      Pages 431-445
    6. E. F. Mammen
      Pages 447-460
    7. M. Dören
      Pages 461-471
    8. V. W. Henderson
      Pages 473-503
    9. M. Oettel
      Pages 505-571
  5. Part 8: Comparative Endocrinology

  6. Back Matter
    Pages 665-683

About this book

Introduction

For many years, Springer has been publishing an impressive series of textbooks of pharmacology which have set standards in medical science. Surprisingly, an extensive overview of the current state of the art in research on estrogens and anti estrogens was still lacking. The present two volumes on estrogens and anti estrogens provide a comprehensive review of a field of research in which remarkable progress has been made over the past few years. New insights into the mechanisms of steroid hormone action resulted in a tremendous number of pUblications from which new principles of preventive and therapeutic appli­ cations of estrogens and anti estrogens emerged. Although various electronic data bases provide easy access to this copious information, there was a clear necessity for a monograph-style textbook which assesses and summarizes current knowledge in this rapidly expanding field of research. It should be noted, however, that, due to this dynamic development, it is barely possible to comprehensively update every aspect of basic and clinical knowledge on estro­ gens and antiestrogens. Thus, the intention of the editors was to provide the reader with an overview of the "classic" and most recently explored areas of research and stimulate future interests in basic and applied endocrinology. Estrogens were among the first steroid hormones described in the scientific literature. Since they were first isolated, since the chemical, synthesic and pharmacological characterization of naturally occurring estrogens and, later on, of orally active derivatives, estrogen research has produced continu­ ously hallmark results in reproductive endocrinology worldwide.

Keywords

Estrogens Hydra Lipid Vivo antiestrogens enzymes influence metabolism pathophysiology physiology

Authors and affiliations

  • Michel Oettel
    • 1
  • Ekkehard Schillinger
    • 2
  1. 1.Jenapharm GmbH & Co. KGJenaGermany
  2. 2.Schering AktiengesellschaftGermany

Bibliographic information

  • DOI https://doi.org/10.1007/978-3-642-60107-1
  • Copyright Information Springer-Verlag Berlin Heidelberg 1999
  • Publisher Name Springer, Berlin, Heidelberg
  • eBook Packages Springer Book Archive
  • Print ISBN 978-3-642-64261-6
  • Online ISBN 978-3-642-60107-1
  • Series Print ISSN 0171-2004
  • Series Online ISSN 1865-0325
  • Buy this book on publisher's site
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