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Immune Response in the Critically Ill

  • Book
  • © 2002

Overview

Editors:
  1. John C. Marshall

    1. Department of Surgery Interdepartmental Division of Critical Care Medicine, Toronto General Hospital University of Toronto, Toronto, Canada

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  2. Jonathan Cohen

    1. Department of Infectious Diseases & Microbiology Division of Investigative Science, Imperial College School of Medicine Hammersmith Hospital, London, UK

    View editor publications

    You can also search for this editor in PubMed   Google Scholar

Part of the book series: Update in Intensive Care Medicine (UICMSOFT)

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About this book

This book brings together basic scientists or clinicians from a variety of different backgrounds - immunology, infectious diseases or critical care - who share a common interest in understanding the changes that occur in immune responses in sepsis. It provides an up-to-date and unrivalled synthesis of current research in this rapidly developing field.

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Table of contents (27 chapters)

  1. Front Matter

    Pages I-XIV
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  2. The Four Ds of the Danger Model: Distress, Damage, Destruction, and Death

    • P. Matzinger
    Pages 1-11

  3. The Immune Response in Critical Illness: Excessive, Inadequate or Dysregulated

    • J. L. Vincent
    Pages 12-21

  4. Genomics of the Sepsis Syndrome

    • S. J. H. van Deventer, P. Stokkers
    Pages 22-36

  5. The Pro-Inflammatory Cytokine Cascade

    • J.-M. Cavaillon, M. Adib-Conquy
    Pages 37-66

  6. Inhibitory Cytokines

    • T. Calandra, D. Heumann
    Pages 67-83

  7. Interleukin-1β and Interleukin-18: Two Cytokine Precursors for Interleukin-1 β Converting Enzyme (Caspase-1)

    • C. A. Dinarello
    Pages 84-96

  8. Bacterial Toxins Induce Selective Cytokine Patterns In Vivo and In Vitro

    • J. Andersson, U. Andersson
    Pages 97-115

  9. The Acute Phase Response and Enhancing Resistance to Bacterial Infection

    • M. Noursadeghi, J. Cohen
    Pages 116-139

  10. Cytokines as Mediators of Lung Innate Immunity

    • T. J. Standiford, B. Merhad, W. C. Tsai
    Pages 140-154

  11. Fetuin Opsonizes Macrophage-Deactivating Cations

    • H. Wang, K. J. Tracey
    Pages 155-163

  12. LPS Receptors

    • E. Lien, H. Heine, D. T. Golenbock
    Pages 164-172

  13. Regulation of Cellular Responses to Bacterial Endotoxin

    • R. J. Ulevitch
    Pages 173-181

  14. The Role of Nitric Oxide in the Initiation of Inflammation in Shock

    • R. T. Villavicencio, T. R. Billiar
    Pages 182-189

  15. Regulation of Neutrophil Activation in Acute Lung Injury and SIRS

    • J. Kruger, Q. Dong, G. Downey
    Pages 190-209

  16. Neutrophils and Acute Lung Injury

    • C. Haslett, S. Donnelly, N. Hirani
    Pages 210-225

  17. Lymphocyte Activation, Anergy, and Apoptosis in Polymicrobial Sepsis

    • A. Ayala, C. S. Chung, G. Y. Song
    Pages 226-246

  18. Trauma Mediators Favor Differentiation of Monocytes to Macrophage Rather Than to Dendritic Cells

    • C. L. Miller-Graziano, A. K. De, K. Kodys
    Pages 247-263

  19. Programmed Cell Death (Apoptosis) and the Immunologic Derangements of Critical Illness

    • R. Taneja, L. Yue, J. C. Marshall
    Pages 264-279

  20. The Interaction Between the Coagulation System and the Systemic Inflammatory Mediators

    • S. M. Opal
    Pages 280-291
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Editors and Affiliations

  • Department of Surgery Interdepartmental Division of Critical Care Medicine, Toronto General Hospital University of Toronto, Toronto, Canada

    John C. Marshall

  • Department of Infectious Diseases & Microbiology Division of Investigative Science, Imperial College School of Medicine Hammersmith Hospital, London, UK

    Jonathan Cohen

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