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Toxoplasma gondii

  • Book
  • © 1996

Overview

Editors:
  1. Uwe Gross

    1. Institute for Hygiene and Microbiology, University of Würzburg, Würzburg, Germany

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Part of the book series: Current Topics in Microbiology and Immunology (CT MICROBIOLOGY, volume 219)

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Table of contents (23 chapters)

  1. Front Matter

    Pages I-XI
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  2. Population Structure of Toxoplasma gondii: Implications of Clonality

    1. Front Matter

      Pages 1-1
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    2. Genetic Basis of Pathogenicity in Toxoplasmosis

      • L. D. Sibley, D. K. Howe
      Pages 3-15

    3. DNA Polymorphisms Associated with Murine Virulence of Toxoplasma gondii Identified by RAPD-PCR

      • Z.-G. Guo, A. M. Johnson
      Pages 17-26

    4. Biodiversity in Toxoplasma gondii

      • M. L. Dardé
      Pages 27-41

  3. The Parasite: From Antigens to Genes

    1. Front Matter

      Pages 43-43
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    2. The Major Surface Proteins of Toxoplasma gondii: Structures and Functions

      • S. Tomavo
      Pages 45-54

    3. Toxoplasma gondii Microneme Proteins: Gene Cloning and Possible Function

      • M. N. Fourmaux, N. Garcia-Réguet, O. Mercereau-Puijalon, J. F. Dubremetz
      Pages 55-58

    4. Role of Secretory Dense Granule Organelles in the Pathogenesis of Toxoplasmosis

      • M.-F. Cesbron-Delauw, L. Lecordier, C. Mercier
      Pages 59-65

    5. Serological Recognition of Toxoplasma gondii Cyst Antigens

      • J. E. Smith, G. McNeil, Y. W. Zhang, S. Dutton, G. Biswas-Hughes, P. Appleford
      Pages 67-73

    6. Toxoplasma gondii: Kinetics of Stage-Specific Protein Expression During Tachyzoite-Bradyzoite Conversion in Vitro

      • M. Soête, J. F. Dubremetz
      Pages 75-80

    7. Bradyzoite-Specific Genes

      • W. Bohne, S. F. Parmley, S. Yang, U. Gross
      Pages 81-91

  4. The Host: Immunogenetics and Immune Response

    1. Front Matter

      Pages 93-93
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    2. Immunogenetics in Pathogenesis of and Protection Against Toxoplasmosis

      • R. McLeod, J. Johnson, R. Estes, D. Mack
      Pages 95-112

    3. Cells and Cytokines in Resistance to Toxoplasma gondii

      • C. A. Hunter, Y. Suzuki, C. S. Subauste, J. S. Remington
      Pages 113-125

    4. Role of Macrophage-Derived Cytokines in the Induction and Regulation of Cell-Mediated Immunity to Toxoplasma gondii

      • R. T. Gazzinelli, D. Amichay, T. Sharton-Kersten, E. Grunwald, J. M. Farber, A. Sher
      Pages 127-139

    5. Role of Nitric Oxide-Induced Immune Suppression in Toxoplasmosis During Pregnancy and in Infection by a Virulent Strain of Toxoplasma gondii

      • E. Candolfi, O. Villard, M. Thouvenin, T. T. Kien
      Pages 141-154

    6. Cytokine Production by Human Cells after Toxoplasma gondii Infection

      • H. Pelloux, P. Ambroise-Thomas
      Pages 155-163

    7. Characterization of Human T Cell Clones Specific for Toxoplasma gondii

      • V. Pistoia, P. Facchetti, F. Ghiotto, M. F. Cesbron-Delauw, I. Prigione
      Pages 165-173

    8. Toxoplasma Proteins Recognized by Protective T Lymphocytes

      • H. G. Fischer, G. Reichmann, U. Hadding
      Pages 175-182
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Keywords

About this book

For years, toxoplasmosis has been known as disease mostly affecting newborns. Since immunocompromised patients (AIDS) present a high risk of reactivation of chronic toxoplasmosis this parasitic disease has gained increasing interest. Besides presenting clinical and therapeutical concepts, this volume provides current knowledge about genetics and immunology of T. gondii and the interaction with its 'host'. Since in vivo and in vitro models of toxoplasmosis exist, and genetic manipulation has become possible, this protozoan parasite has recently been accepted as a model for understanding the pathogenesis and persistance of other intracellular parasites. The articles of the book compromise both reviewing current concepts and reporting on yet unpublished results of leading scientists in this field.

Editors and Affiliations

  • Institute for Hygiene and Microbiology, University of Würzburg, Würzburg, Germany

    Uwe Gross

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