Overview
- Consolidates the current research and literature into a clinically relevant text
- Covers neurobiology as well as clinical neuroscience of inflammation in Parkinson's Disease
- Fulfills the current need for a text that emphasizes inflammation and its role in neurodegeneration
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Table of contents (9 chapters)
Keywords
- Biologic markers, PET imaging, neuroinflammation,
- Cytokine, nitric oxide, anti-inflammatories, animal models
- Neurodegeneration, microglia, oligodendrocytes, astrocytes,
- Neuropathology, acute and chronic inflammation,
- Parkinson's disease, inflammation, translational neurobiology
- Pathologic findings, MPTP toxicity, epidemiology
About this book
Parkinson’s Disease (PD) is a progressive neurodegenerative disease with a prevalence of 0.1% of the global population, and 5-10% patients are under 40 years of age. Several text books have been published on various aspects of PD to date, including research and clinical aspects. However these do not emphasize the inflammatory pathways and pathways of neurodegeneration in PD. Inflammation in Parkinson’s Disease brings advances in research together with current literature and evidence. This concise volume covers the fundamentals of neuroimmunology and inflammatory models, the interactions between pathways of neurodegeneration and follows the concept of research work undertaken from basic science to clinical trials. Researchers, clinicians, and students interested in Parkinson's Disease are provided with a comprehensive view of translational research methods and an insight needed for developing future therapies aimed at disease modulation.
Reviews
“This is an excellent monograph about inflammatory mechanics of PD. … this is an excellent book for neurologists, neurosurgeons, residents, and medical students. Neuromuscular and Stereotactic Fellows will also like this book.” (Joseph J. Grenier, Amazon.com, March, 2016)
Editors and Affiliations
About the editor
Madhavi Thomas is currently a Neurologist and the President of the North Texas Movement Disorders Institute in Colleyville, TX. She continues to serve as the Dallas Chapter of the American Parkinson Disease Association's Medical Director and has held faculty positions at Baylor University and UT Southwestern Medical School.
Bibliographic Information
Book Title: Inflammation in Parkinson's Disease
Book Subtitle: Scientific and Clinical Aspects
Editors: Madhavi Thomas
DOI: https://doi.org/10.1007/978-3-319-08046-8
Publisher: Springer Cham
eBook Packages: Medicine, Medicine (R0)
Copyright Information: Springer International Publishing Switzerland 2014
Hardcover ISBN: 978-3-319-08045-1Published: 11 September 2014
Softcover ISBN: 978-3-319-34276-4Published: 17 September 2016
eBook ISBN: 978-3-319-08046-8Published: 27 August 2014
Edition Number: 1
Number of Pages: XVI, 222
Number of Illustrations: 4 b/w illustrations, 13 illustrations in colour
Topics: Neurology, Internal Medicine, Medical Biochemistry
Industry Sectors: Biotechnology, Finance, Business & Banking, Health & Hospitals, Pharma