Overview
- Includes cutting-edge methods and protocols
- Provides step-by-step detail essential for reproducible results
- Contains key notes and implementation advice from the experts
Part of the book series: Methods in Molecular Biology (MIMB, volume 1857)
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Table of contents (18 protocols)
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Front Matter
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Back Matter
Keywords
About this book
This volume explores the latest techniques and approaches used to study this emerging form of cell death. The chapters in this book cover topics such as distinguishing necroptosis from apoptosis; detecting MLKL oligomerization during programmed necrosis; analyzing the RIPK3 necrosome complex; using RIPK1 kinase small molecule inhibitors in studying necroptosis; monitoring RIPK1 phosphorylation in the TNFR1 signaling complex; and assessing in vivo kidney cell death in glomerular injury. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls.
Cutting-edge and thorough, Programmed Necrosis: Methods and Protocols is a valuable resource for technicians, graduate students, postdoctoral fellows, and other scientists who are pursuing studies in this field.
Editors and Affiliations
Bibliographic Information
Book Title: Programmed Necrosis
Book Subtitle: Methods and Protocols
Editors: Adrian T. Ting
Series Title: Methods in Molecular Biology
DOI: https://doi.org/10.1007/978-1-4939-8754-2
Publisher: Humana New York, NY
eBook Packages: Springer Protocols
Copyright Information: Springer Science+Business Media, LLC, part of Springer Nature 2018
Hardcover ISBN: 978-1-4939-8753-5Published: 23 August 2018
Softcover ISBN: 978-1-4939-9384-0Published: 10 December 2019
eBook ISBN: 978-1-4939-8754-2Published: 22 August 2018
Series ISSN: 1064-3745
Series E-ISSN: 1940-6029
Edition Number: 1
Number of Pages: XI, 191
Number of Illustrations: 30 b/w illustrations, 12 illustrations in colour
Topics: Cell Biology
Industry Sectors: Biotechnology, Pharma