Overview
- Editors:
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Michael E. Maragoudakis
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University of Patras Medical School, Patras, Greece
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Pietro Gullino
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University of Turin Medical School, Turin, Italy
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Peter I. Lelkes
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University of Wisconsin Medical School, Milwaukee, USA
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Table of contents (52 chapters)
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Angiogenesis in Disease States
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- Jacqueline B. Weiss, Raj Odedra
Pages 217-230
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- Robert A. Brown, Clive D. Mcfarland, Michael Kayser, S. Yousuf Ali, Barry Mclaughlin, Jacqueline B. Weiss
Pages 231-241
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Promoters and Inhibitors of Angiogenesis
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- Jacqueline B. Weiss, Barry McLaughlin
Pages 243-251
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- S. Kumar, P. Kumar, J. M. Ponting, A. Sattar, P. Rooney, D. Pye et al.
Pages 253-263
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- Christopher Guerin, Rafael J. Tamargo, Alessandro Olivi, Henry Brem
Pages 265-274
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- Michael E. Maragoudakis, Nikos E. Tsopanoglou, Maria Bastaki, George Haralabopoulos
Pages 275-285
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Therapeutical Potential of Promoters and Inhibitors of Angiogenesis
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Methodology
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- T.-P. D. Fan, D.-E. Hu, C. R. Hiley
Pages 317-332
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- Peter I. Lelkes, Mark M. Samet, Carl W. Christensen, David L. Amrani
Pages 339-351
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Abstract of Oral and Poster Presentations
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- H. Drexler, H. Schurch, G. Breier, G. Drexler, W. Risau
Pages 353-354
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- Luc Pardanaud, Francoise Dieterlen-Lièvre
Pages 355-355
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- C. Van Ackern, M. A. Konerding, F. Steinberg, C. Streffer
Pages 359-359
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- Steven Brem, Ana-Maria Tsanaclis, D. Zagzag, S. Gately
Pages 361-362
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- S. Brem, D. Zagzag, A. M. Tsanaclis, S. Gately, J. L. Gross
Pages 363-364
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About this book
Angiogenesis describes the formation of new blood vessels, which arise as outgrowths from existing vessels. In many physiological processes such as ovulation and wound healing angiogenesis is involved for a relatively short time. Otherwise under normal physiological conditions in the adult organism angiogenesis is an extremely slow process. By contrast in certain disease states such as diabetic retinopathy, arthritis, chronic inflammation, hemangiomas, etc., angiogenesis persists and contributes to the pathology of these disease states. Some 50 such "angiogenic diseases" have been described where angiogeneSiS is involved. Also in tumor growth and metastasis angiogenesis is an essential process and precedes neoplastic transformation. Hence, angiogenesis could become an important diagnostic tool and a target for developing therapeutic agents. This book contains the proceedings of the NATO Advanced Study Institute on "Angiogenesis in Health and Disease" held in Porto Hydra, Greece, from June 16-27, 1991. This meeting was a comprehensive review of endothelial cell biology and endothelial cell phenotypic and functional heterogeneity in relation to angiogenesis under physiological and pathological conditions. Numerous in vitro and in vivo models were presented, which are used to study angiogenesis at the molecular and cellular levels and to evaluate chemical compounds or naturally occuring substances for their effect on angiogenesis. The presentations and discussions at this meeting provided an opportunity for the basic science and the clinical disciplines to meet, exchange information and provide future research directions for many investigators engaged in the study of angiogenesis.
Editors and Affiliations
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University of Patras Medical School, Patras, Greece
Michael E. Maragoudakis
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University of Turin Medical School, Turin, Italy
Pietro Gullino
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University of Wisconsin Medical School, Milwaukee, USA
Peter I. Lelkes